Oil-in-Water Nanosized Emulsions for Drug Delivery and Targeting (eBook)

Tamilvanan Shunmugaperumal, PhD, works at the National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, India. His current research focuses on systematic optimization of formula to prepare various pharmaceutical dosage forms such as solid lipid microparticles, nanosized emulsions, and microspheres, where he seeks to exploit the potential of lipid- and polymer-based drug delivery carriers to eradicate infectious biofilm formation associated with both medical devices and human organs.

List of Contributors ix

Foreword xi

Preface xiii

1. Introduction: An Overview of Nanosized Emulsions 1

2. Formulation Development of Oil-In-Water Nanosized Emulsions 19

3. Characterization and Safety Assessment F Oil-In-Water Nanosized Emulsions 69

4. Manufacturing and Positioning (Generations) of Oil-In-Water Nanosized Emulsions 169

5. Biofate of Nanosized Emulsions 225

6. Medical or Therapeutical Applications of Oil-In-Water Nanosized Emulsions 259

Part I: Overview of Tocol-Based Emulsions, Oxygen-Carrying Emulsions, Emulsions With Double or Triple Cargos and Emulsion-Like Dispersions 287

7. Overview of Tocol-Based Emulsions, Oxygen-Carrying Emulsions, Emulsions With Double or Triple Cargos and Emulsion-Like Dispersions 289

7.1. Tocol-Based Nanosized Emulsions 291

7.2. Oxygen-Carrying Emulsions 301

7.3. Nanosized Emulsions For Multiple Medicament Loadings, Imaging, and Theranostic Purposes 321

7.4. Emulsion-Like Dispersions 347

Part II: Selected Case Studies 369

8. Selected Case Studies 371

8.1. Case Study 1 - Cationic Nanosized Emulsions: Narration of Commercial Success 373

8.2. Case Study 2 - Fish Oil-Based Nanosized Emulsions 389

Index 423