Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing (eBook)

This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.

Dr. Pankaj Suman is a Scientist and Principal Investigator at the National Institute of Animal Biotechnology, Hyderabad, India. He did his Bachelors in Veterinary Medicine from Maharashtra Animal and Fishery Sciences University, Nagpur, India and obtained the MS degree from the Indian Institute of Technology Roorkee, Roorkee, India. He did Ph.D. from the National Institute of Immunology, New Delhi. He also worked as visiting scholar at the Friedrich-Schiller University, Jena, Germany (2007-2010). His research experience spans through varying discipline of science pertaining to immunology, reproductive biology, veterinary, and clinical medicine. In the past, he has made a significant contribution in understanding the molecular mechanisms behind the immunological basis of pregnancy, vaccine delivery, and diagnostics. His current research is focused on the development of the biosensing devices for the detection of small molecules (toxins, metabolites etc.) through designing small antibodies and aptamers as a tool for detection. Till now, he has published over 25 research articles in the various reputed journals. He is the recipient of several prestigious fellowships and awards from agencies like the Council of Scientific and Industrial Research, India, Department of Science and Technology, India, United States Department of Agriculture, USA. He is also the recipient of prestigious G. P. Talwar Young Scientist award for outstanding contribution in reproductive health. He has attended several National and International conferences and delivered invited talks.

 

Dr. Pranjal Chandra is currently employed as an Assistant Professor at the School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, India. He earned his Ph.D. from Pusan National University, South Korea and did post-doctoral training at Technion-Israel Institute of Technology, Israel. His research focus is highly interdisciplinary, spanning a wide range in biotechnology, nanobiosensors, material engineering, nanomedicine, etc. He has designed several commercially viable biosensing prototypes that can be operated for onsite analysis for biomedical diagnostics, environmental monitoring, and other point-of-care testing applications. He has published 6 books on various aspects of biosensors / medical diagnostics from IET London, Springer Nature, CRC press USA. He has also published over 85 journal articles in topmost journals of his research area including; Biosensors and Bioelectronics, Analytical Chemistry, Biomaterials, Chemical Communications, Electroanalysis, etc. His work has been greatly highlighted in over 300 topmost news agencies globally including Rajya Sabha TV, DD Science, Science Trends USA, Nature India, Vigyan Prasar, Global Medical Discovery; Canada, APBN Singapore, Business Wire; Dublin, etc. He is a recipient of many prestigious  awards and fellowships such as; DST Ramanujan fellowship (Government of India);  Early Carrier Research Award (DST, Government of India); Brain Korea -21 and National Research Foundation fellowship, South Korea; Technion post-doctoral fellowship, Israel; NMS Young scientist award, Biotech Research Society India Young Scientist Award, Young Engineers Award 2018, RSC Highly Cited Corresponding Author Award (general chemistry); ACS / Elsevier Outstanding Reviewer Awards, etc. He is a reviewer of over 50 international journals and expert project reviewer of various national/international funding agencies. He is Associate Editor of Sensors International and an editorial board member of a Materials Science for Energy Technologies by KeAi and Elsevier, World journal of methodology, USA;  Frontiers of Biosciences, USA; Reports in Physical Sciences, Singapore. 

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This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.