Regulating with RNA in Bacteria and Archaea (eBook)

Gisela Storz is an NIH Distinguished Investigator in the Eunice Kennedy Shriver National Institute of Child Health and Human Development in Bethesda, Maryland. She carried out graduate work with Dr. Bruce Ames at the University of California, Berkeley and postdoctoral work with Dr. Sankar Adhya at the National Cancer Institute and Dr. Fred Ausubel at Harvard Medical School. As a result of the serendipitous discovery of the peroxide-induced OxyS RNA in E. coli, one of the first small, regulatory RNAs to be found, much of the work in her lab has focused on the genome-wide identification of small RNAs and their characterization. Kai Papenfort is a Professor of Microbiology at the Ludwig Maximilians University of Munich, Germany. He received a diploma in biology from the University of Marburg and carried out graduate work with Dr. Jörg Vogel at the Max Planck Institute for Infection Biology and the Humboldt University of Berlin. In his postdoctoral work at the University of Würzburg and Princeton University, Dr. Papenfort studied the regulatory functions of small RNA in bacterial pathogens and their involvement in bacterial communication processes such as quorum sensing. His laboratory focuses on the molecular mechanisms underlying the regulation by small RNAs in the major human pathogen, Vibrio cholerae.

Finally! One spectacular volume provides us
all we need to educate ourselves in the fascinating world of regulatory RNAs in
bacteria and archaea. From the genetics to the biochemistry to the mechanisms
to the structures to the physiology to the networks to the challenges for the
future--it's all here--laid out for us in exceptional form by the world's key
experts. This volume is an eye-opening must read about one of microbiology's
most exciting emerging fields.

-Bonnie L. Bassler, Ph.D.lang=EN-CA>, HHMI Investigator, Squibb Professor and Chair of the Department of
Molecular Biology, Princeton University