SERS for Point-of-care and Clinical Applications

Andrew Fales is a Staff Fellow in Biomedical Engineer and works in the Division of Biomedical Physics, Office of Science and Engineering Laboratories at the Center for Devices and Radiological Health, U.S. Food and Drug Administration.

Part 1: Background 1. Label-free SERS in biomedical applications 2. SERS probes and labels for biomedical applications

Part 2: Point-of-Care applications 3. SERS biosensors for infectious disease diagnosis 4. SERS-based molecular sentinels for nucleic acid detection 5. Quantitative determination of cellular biomarker expression for identification of effective cancer treatments using SERS biosensors 6. Nanoporous gold substrates for SERS-based in vitro diagnostics

Part 3: (pre-)Clinical applications 7. SERS detection of oral and GI cancerous tissues 8. Surface-enhanced spatially offset Raman spectroscopy for breast cancer detection 9. Brain tumor delineation using gold nanostar SERS tags 10. Multiplexed cancer immunoimaging using SERS