Yeast Cell Surface Engineering -

Yeast Cell Surface Engineering (eBook)

Biological Mechanisms and Practical Applications

Mitsuyoshi Ueda (Herausgeber)

eBook Download: PDF
2019 | 1st ed. 2019
VIII, 185 Seiten
Springer Singapore (Verlag)
978-981-13-5868-5 (ISBN)
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96,29 inkl. MwSt
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This book provides a detailed and up-to-date overview of all aspects of yeast cell surface engineering, including fundamental principles, practical strategies for the construction of engineered yeasts, as well as medical and industrial applications. The technique makes it possible to add eukaryotic modifications to the surface-displayed proteins/peptides, which is of significant value in basic and applied research. Generally referred to as an arming (molecular display) technology, it allows yeast to be used as a whole-cell biocatalyst for a range of purposes, including bio-energy production, pollutant removal, recovery of rare metal ions, and preparation of functional cells, all of which are comprehensively covered in the book. Among the medical applications discussed are in vitro antibody preparation and the production of oral vaccines. In addition, it presents the latest advances in protein engineering and high-throughput screening for directed evolution of enzymes. The book enables graduate students and researchers to gain a deeper, comprehensive understanding of the technology, and offers further inspiration for researchers and industrial experts in this rapidly evolving field.




Prof. Mitsuyoshi Ueda 

Laboratory of Biomacromolecular Chemistry, Division of Applied Life Sciences, Department of Applied Biochemistry, Graduate School of Agriculture, Kyoto University, Japan


This book provides a detailed and up-to-date overview of all aspects of yeast cell surface engineering, including fundamental principles, practical strategies for the construction of engineered yeasts, as well as medical and industrial applications. The technique makes it possible to add eukaryotic modifications to the surface-displayed proteins/peptides, which is of significant value in basic and applied research. Generally referred to as an arming (molecular display) technology, it allows yeast to be used as a whole-cell biocatalyst for a range of purposes, including bio-energy production, pollutant removal, recovery of rare metal ions, and preparation of functional cells, all of which are comprehensively covered in the book. Among the medical applications discussed are in vitro antibody preparation and the production of oral vaccines. In addition, it presents the latest advances in protein engineering and high-throughput screening for directed evolution of enzymes. The book enables graduate students and researchers to gain a deeper, comprehensive understanding of the technology, and offers further inspiration for researchers and industrial experts in this rapidly evolving field.
Erscheint lt. Verlag 23.4.2019
Zusatzinfo VIII, 185 p. 76 illus., 41 illus. in color.
Sprache englisch
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Medizin / Pharmazie Pflege
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Mykologie
Naturwissenschaften Biologie Zellbiologie
Technik Medizintechnik
Technik Umwelttechnik / Biotechnologie
Schlagworte antibodies • Antibody • Aquatic purification • Arming technology • Biofuel production • bioremediation • cell factory • Combinatorial engineering • Enzyme evolution • Eukaryotic secretory pathways • Molecular display • Peptide • pollutant removal • Protein • resource recovery • Surface displayed protein • Vaccine • Whole-cell biocatalyst
ISBN-10 981-13-5868-0 / 9811358680
ISBN-13 978-981-13-5868-5 / 9789811358685
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