Radionanomedicine (eBook)

Dong Soo Lee, M.D.Ph.D. is a nuclear medicine physician and nanomedicine expert who is a professor of nuclear medicine in Seoul National University (SNU) and SNU hospital since 1990. He is also a professor and chairman of the department of molecular medicine and biopharmaceutical sciences of SNU. He has implemented the concept of ‘Radionanomedicine’ which takes the advantage of tracer principle of nuclear medicine using trace amount of materials and enabling tracer kinetic studies  for nanomaterial use in vivo. He is currently the director of BioMAX/N-Bio Institute of SNU to practice and promote bio convergence approaches of innovative developments of fundamental sciences/engineering to clinical application. He is past-president of Korean Society for Nanomedicine and past-president of Korean Society of Nuclear Medicine as well as past-president of Korean Society of Human Brain Mapping. As a nuclear medicine physician, he specialized in nuclear cardiology and neurology as well as molecular imaging (in vitro and preclinical) and radionanomedicine. He is a graduate of 1982 from SNU, Korea as an MD and received PhD from the same university SNU in 1990 and served as faculty of nuclear medicine in SNU since then. He has authored more than 300 articles in peer-reviewed SCI journals, and edited several books including the ‘Atlas of PET/MRI, PET/CT and SPECT/CT’ in 2016 by Springer-Nature. He is the Editor-in-Chief of ‘Nuclear Medicine Molecular Imaging’ since 2015 and has served in the Editorial Board of Journal of Nuclear Medicine, European Journal of Nuclear Medicine and Molecular Imaging, Journal of Nuclear Cardiology and European Journal of Nanomedicine. He is a Fellow of American College of Cardiology and member of Korean Academy of Science and Technology since 2006, and member of National Academy of Medicine of Korea since 2015.

Exogenous Radionanomedicine -       Inorganic Nanomaterials                   Weibo Cai (U Wisconsin, USA) -       Organic Nanomaterials: Radioliposome, Albumin, Dendrimer, Polymer (PLGA, etc).                            Keon Wook Kang (Seoul Nat’l U, Korea)   Endogenous Radionanomedicine -       Extracellular Vesicles                            Yong Song Gho (POSTECH) -       Radiolabelling         Hong Yoon Choi & Do Won Hwang (Seoul Nat’l U) -       Biodistribution and Imaging         Hong Yoon Choi &  Dong Soo Lee (SNU, Korea)           -       Validation of Therapeutic Potential   Dong Soo Lee (SNU, Korea)   Surface modification and Radiolabeling -       Surface modification                                Hao Hong (U Michigan, USA) -       Radiolabeling method: Core/Surface labelling, Chemical and Physical labelling,  Jonathan F Lovell (U Buffalo) or Jae Min Jeong (SNU Korea) -       Click chemistry  Yun-Sang Lee (SNU) & Dexing Zeng (U Pittsburgh)   Targeted Delivery with Click Chemistry -       Targeting molecule and nano-platform    Yun-Sang Lee (SNU, Korea) -       Preservation of ligand functionality by click chemistry -                                                              Bart Cornelissen (U Oxford, UK) -       Bioorthogonal reaction                    Dong Wook Kim (Inha U, Korea)                           In vivo Biodistribution using PET and SPECT -       Preclinical PET/CT, SPECT/CT, and PET/MRI  -                    Hyung Jun Im (U Wisconsin) & Gi Jeong Cheon (SNU Korea) -       Tracer kinetic                Jae Sung Lee & Dong Soo Lee (SNU, Korea)   Factors and Results Affecting Biodistribution -       Size, charge and shape           -       PEGylation and the similar       Mailander (U Mainz, Germany) -       Corona and its consequences     Kenneth Dawson (U Dublin, Ireland) -       Excretion and clearance   Hyung Jun Im & Dong Soo Lee (SNU Korea)   Immune Responses to Nanomaterials -       IgM responses       Ishida (U Tokushima, Japan) -       Innate Immunity      Bengt Fadeel (Karolinska University, Sweden) -       CARPA                 Szebeni (Semmelweiss U, Hungary)        Molecular Imaging            Dong Soo Lee (SNU, Korea)