Regenerative Medicine: Laboratory to Clinic (eBook)

Dr. Asok Mukhopadhyay has just retired from the very prestigious National Institute of Immunology, New Delhi after more than 25 years of service as a Scientist & Principle Investigator. He received his PhD from the Indian Institute of Technology, New Delhi and worked as a Post-Doctoral Research Fellow at MD Anderson Cancer Center, Houston, Texas, USA. His main area of research is stem cells in regenerative medicine. He has published 75 research papers, contributed to 7 book chapters and has also written the textbook “Animal Cell Technology” [Published by IK International, New Delhi; ISBN: 978-81-89866-96-9 (2009)]. Further, he holds 2 Indian patents. Dr. Mukhopadhyay is a member of the Scientific Advisory Committee of several leading Indian institutions, as well as the Task Force on ‘Stem Cells Research and Regenerative Medicine’- Department of Biotechnology, Government of India. He also serves as a reviewer for various reputed journals such as Tissue Engineering, World Journal of Stem Cell Research, Biotechnology & Bioengineering, and Stem cells and Development.

Physical forces that regulate stem cell fate.- Pluripotent stem cells: its potential applications.- Unraveling the role of long-non coding RNAs in pluripotent stem cells-based neuronal commitment and neurogenesis.- Control of quiescence in adult stem cells.- Etiology and treatment of osteoarthritis: A developmental biological perspective.- Differences in cell populations and expression of soluble mediators between normal wound healing and healing in the diabetic.- MSC-derived exosomes as tools in regenerative medicine.- Mixing of different batches of cells permits better therapeutic potential of MSCs.- Blood to blood: new candidate for regenerative medicine.- HSC based gene therapy for blood diseases.- Allogeneic stem cell transplantation including haplo-identical stem cell transplants.- Mesenchymal stem cells and transplantation tolerance.- Ideal stem cell candidate for regenerative medicine.- Pre-clinical/clinical study on idiopathic pulmonary fibrosis.- Comparative analysis between ES and iPS cells for use in regenerative medicine: scope, advantage and safety.- Regeneration of lacrimal gland: potential and progress.- Clinical trials in cardiac regeneration using adult stem cells: Current and future prospects.- Tissue engineering for the treatment of in large bone defect.- Corneal Regeneration: Current status and future directions.- Cell therapy for retinal regeneration: current progress and future challenges.- Vaculogenesis: Importance in regeneration of solid organs.- Cord blood banking in India and the global scenario.- Prospects and retrospect of clinical applications of stem cell in veterinary sciences.- Engineering of scaffolds for soft tissue engineering.- 3D bioprinting of tissue.- Tissue engineering: Cell, scaffold and growth factor based strategies.- Pre-clinical trial:  A bottleneck that impedes development of regenerative medicine.- Stem cell research work ethics and Indian stem cell research policy.