Compendium of Biophysics (eBook)

Andrey B. Rubin is a professor of biophysics at Lomonosov Moscow State University in the Department of Biophysics. Born in Russia, he is chair of the National Committee for Biophysics in the Russian Academy of Science. He has been head of the Department of Biophysics at MSU, Governor of the Task Force on Education in Biophysics, and a member of the RAS Council on Space Biology and Biological Membranes since 2005. He has received many awards for his contributions to the science of biophysics, and he holds many patents and inventions, as well as having been the author of numerous papers. He is also on the editorial board of the journal, Biophysics, in the Russian language.

Introduction xv

PART I BIOPHYSICS OF COMPLEX SYSTEMS

I. Kinetics of Biological Processes 3

1 Qualitative Methods for Studying Dynamic Models of Biological Processes 5

2 Types of Dynamic Behavior of Biological Systems 17

3 Kinetics of Enzyme Processes 29

4 Self-Organization Processes in Distributed Biological Systems 45

II. Thermodynamics of Biological Processes 77

5 Thermodynamics of Irreversible Processes in Biological Systems Near Equilibrium (Linear Thermodynamics) 79

6 Thermodynamics of Systems Far From Equilibrium (Nonlinear Thermodynamics) 91

PART II MOLECULAR BIOPHYSICS

III. Three-dimensional Organization of Biopolymers 99

7 Three-dimensional Confi gurations of Polymer Molecules 101

8 Different Types of Interactions inMacromolecules 109

9 Conformational Energy and Three-dimensional Structure of Biopolymers 117

IV. Dynamic Properties of Globular Proteins 153

10 Protein Dynamics 155

11 Physical Models of Dynamic Mobility of Proteins 187

PART III BIOPHYSICS OF MEMBRANE PROCESSES

V. Structure-functional Organization of Biological Membranes 227

12 Molecular Organization of Biological Membranes 229

13 Conformational Properties of Membranes 247

VI. Transport of Substances and Bioelectrogenesis 261

14 Nonelectrolyte Transport 263

15 Ion Transport. Ionic Equilibria 269

16 Electrodiffusion Theory of Ion Transport Across Membranes 281

17 Induced Ion Transport 287

18 Ion Transport in Channels 295

19 Ion Transport in Excitable Membranes 319

20 Active Transport 339

VII. Energy Transformation in Biomembranes 349

21 Electron Transport and Energy Transformation in Biomembranes 351

22 Physics of Muscle Contraction, Actin-Myosin Molecular Motor 365

23 Biophysics of Processes of Intracellular Signaling 379

VIII. Electronic Properties of Biopolymers 403

24 Fundamentals of Quantum Description of Molecules 405

25 Mechanisms of Charge Transfer and Energy Migration in Biomolecular Structures 425

26 Mechanisms of Enzyme Catalysis 481

27 Energy Transformation in Primary Processes of Photosynthesis 505

28 Electron-Conformational Interactions in Primary Processes of Photosynthesis 547

X. Primary Processes in Biological Systems 579

29 Photo-conversions of Bacteriorhodopsin and Rhodopsin 581

30 Photoregulatory and Photodestructive Processes 607

Further Reading 633

Index 635