Biodrug Delivery Systems
CRC Press (Verlag)
978-1-138-11679-5 (ISBN)
Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses components of successful formulation, delivery, and production of biodrugs, which include sophisticated plants and complex processes, a well-trained and knowledgeable staff, and proper quality control. In addition, the authors examine:
ADME (Absorption, Metabolism, Distribution, and Elimination of biodrugs)
Directing and influencing the successful development of currently marketed best-selling biodrugs
Routes of administration
Mechanisms of biodrug absorption
Alternative possibilities for drug delivery routes
Formulationson the market from the perspective of industry personnel involved in biodrug development
Mariko Morishita, Kinam Park
1. Overview of Biodrug delivery system. 2. Issues in Biodrug delivery system. 3. Pharmacokinetic consideration of Biodrugs. Specific Route of Delivery. 1. Parenteral delivery. 2. Brain delivery. 3. Ocular delivery. 4. Nasal delivery. 5. Buccal delivery. 6. Pulmonary delivery. 7. Transdermal delivery. 8. Colon delivery. 9. Oral delivery. 10. Cellular delivery. Delivery Systems. 1. Targeting: PK consideration. Monoclonal antibody. Receptor-mediated endocytosis. 2. Bioadhesive delivery system. 3. Modified release delivery system. 4. Nanoparticulate delivery system. 5. Lipid-based delivery system. 6. Implantable delivery system. 7. Modifying the physiochemical nature of Biodrugs. 8. Regulatory perspective of Biodrug development. Development of Biodrug Products. 1. Leuplin. 2. ANP (atrial natriuretic peptide). 3. Amylin and GLP-1 agonists. 4. GHRP-2 (growth hormone releasing peptide. 5. Endothelin receptor antagonist. 6. Angiotensin II receptor antagonist. 7. Insulin (inhalation). 8. Calcitonin (nasal, etc.). 9. Sandstatin LAR. 10. Interferon. 11. Vaccine. Perspective of Biodrug Products.
| Erscheinungsdatum | 25.07.2017 |
|---|---|
| Reihe/Serie | Drugs and the Pharmaceutical Sciences |
| Zusatzinfo | 90 Illustrations, black and white |
| Verlagsort | London |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 453 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Medizin / Pharmazie ► Pharmazie | |
| Naturwissenschaften ► Biologie | |
| Technik | |
| ISBN-10 | 1-138-11679-3 / 1138116793 |
| ISBN-13 | 978-1-138-11679-5 / 9781138116795 |
| Zustand | Neuware |
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