Mechanical Circulatory and Respiratory Support

Shaun D. Gregory has Bachelor, Masters and PhD degrees in medical engineering and has completed research in some of the world’s leading cardiovascular device research institutes. He has multiple research publications, grants, patents and awards. Shaun is a research fellow in the Griffith University School of Engineering and directs the Innovative Cardiovascular Engineering and Technology Laboratory, a world-class research facility with a team of biomedical, mechanical and electrical engineers who work alongside clinicians to develop devices to support the heart and lungs. John Fraser is the Founder and Director of the Critical Care Research Group, Director of the ICU at St Andrew’s War Memorial Hospital, President of AP-ELSO and a Professor of Medicine at the University of Queensland. His research spans across several disciplines including medicine, biomedical science, engineering and more. John’s work has changed clinical practice on a global scale on several occasions, while his passion for innovation continues to change the scientific fields that he works in. Dr. Fraser has won numerous prizes and fellowships for his research, and contributed to the education of countless clinicians, scientists and engineers. Michael C. Stevens has bachelor and PhD degrees in biomedical engineering and has a special research interest in control of mechanical devices that support the heart. He has worked in cardiovascular research institutes in Australia and in the United States and is now employed by the Graduate School of Biomedical Engineering at the University of New South Wales, the largest biomedical engineering school in the southern hemisphere.

Part 1: Heart Failure and Non-Device Treatment 1. The Descent into Heart and Lung Failure 2. Optimizing the Patient and Timing of the Introduction of Mechanical Circulatory and Extracorporeal Respiratory Support 3. Heart and Lung Transplantation

Part 2: Types of Cardiovascular Devices 4. First Generation Ventricular Assist Devices 5. Second Generation Ventricular Assist Devices 6. Third Generation Ventricular Assist Devices 7. Biventricular Assist Devices 8. Total Artificial Hearts 9. Extracorporeal Membrane Oxygenation 10. Pediatric devices

Part 3: Pump Design 11. Hydraulic Design 12. Motor design 13. Impeller suspension 14. Pulsatile vs Continuous Flow 15. Preclinical Evaluation

Part 4: Implantation and Medical Management 16. Surgical Implantation 17. Complications of Mechanical Circulatory and Respiratory Support 18. Medical Management of the Supported Patient

Part 5: Physiological Interaction Between Devices and Patient 19. Cannula Design 20. Blood-Device Interaction 21. Physiological Control

Part 6: Physical Interface/Interface Between Implantable Device and Clinician/Patient 22. Percutaneous and Transcutaneous Connections 23. Wearable Systems

Part 7: Route to Market (and staying there!) 24. Route to Market 25. Cost effectiveness

Part 8: Summaries 26. The Past, Present and Future