Essentials of Medicinal and Process Chemistry

Section A - Cell. Structure and Function. Proteins and Amino Acids. Structure and Function. Purification. Chromatography and Electrophoretic Techniques. Enzymes. Introduction. Enzyme Activity. Kinetics of Enzymatic Reactions. The Immune System. Overview. Signal Transduction. Protein Synthesis. Genetic Code. Protein Synthesis Targeting and Post-translational Glycosylation.Section B. - Medicinal Chemistry. Historical Background Perspective. Modern Drug Development. Drug Design. Rational Drug Design. From the Lab to the Cabinet: The Journey of a Drug. Drug Administration and Kinetics. Drug Distribution. Drug Metabolism and Elimination. Drug Dynamics. Infectious Diseases. Non-steroidal Anti-inflammatory Drugs. Cancer Chemotherapy. Antidiabetics. Anti-AIDS and Antiviral Agents. Anti-estrogens. Neuromuscular Disorders and Central Nervous System Stimulants. Cardiovascular Drugs Section C - Process Chemistry. Regulatory Implications. Route Selection. Milestones in Process Development. Analytical Method Development. Work Up. Solvent Effects. Reagent Selection. Scale Up. Basic Planning. Equipment. Some Chemical Engineering Concepts. Process Safety. Process Development of Selected Compounds. Statistical Tools (DOE) in Process Development. Process Analytical Technologies in Process Development. Crystallization Polymorphism. Salt Selection. Green Chemistry.