Biofilms and Implantable Medical Devices

Dr. Ying Deng is an Associate Professor in the Department of Biomedical Engineering at the University of South Dakota (USD). Dr. Deng has authored or co-authored various articles in leading journals, exploring biomaterial applications, especially tissue engineering, and approaches to control biomaterial-related biofilm formation. She has co-authored a book chapter, patents, and has made dozens of presentations at national and international conferences. She has received research funding for multifunctional (biocompatible and antimicrobial) biomaterial development from the South Dakota Board of Regents (SDBOR), the United States Department of Defense, and the National Institutes of Health. In addition, she is currently serving as the Chair of the Sioux Valley Local Section of the American Chemical Society. Her research interests include the development of biocompatible and antimicrobial materials, tissue engineering, drug delivery systems, and surface modification and characterization of biomedical implants and devices. Mr. Wei Lv is a graduate student in the Department of Biomedical Engineering at the University of South Dakota (USD). He received his Master’s degree in Biomedical Engineering from the University of South Dakota in 2012 and a Bachelor’s degree in Biotechnology from Heilongjiang University, China in 2009. He has around five years of experience in the development of antimicrobial technologies, including Chitosan, quaternary ammonium and N-halamines biomaterials, etc. His researches have been published in peer-reviewed journals, including Journal of Biomedical Materials Research Part A, Journal of Materials Science, and Biomaromolecules. His works have also been exhibited in a variety of national and international conferences. His current major research interests are focused on developing antimicrobial biomaterials for drug delivery, tissue engineering scaffolds and biomedical implants and devices. In addition, he has been invited to review manuscripts for leading journals, such as PLOS ONE and Nature Communications. He is a recipient of USD Research & Creative Activity Grants in 2014. He has been serving as a USD student chapter of the Society for Biomaterials committee member since 2010. Currently, He is the Chair for the USD student chapter of the Society for Biomaterials.

Part One. Fundamentals and properties of biofilms

1. Overview of biofilm-related problems in medical devices

2. Properties of biofilms developed on medical devices

3. Adhesion of bacteria to surfaces and biofilm formation on medical devices

4. Antimicrobial resistance of biofilms in medical devices

Part Two. Biofilm-related infections in medical devices

5. Biofilms on dental implants

6. Biofilm on bone repair devices

7. Prevention of biofilm formation by material modification

8. Detection of bacterial adherence and biofilm formation on medical surfaces

9. Alternative strategies to reduce the incidence of severe infections