Biological Effects of Metal Nanoparticles (eBook)

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2016 | 1st ed. 2016
XVI, 292 Seiten
Springer International Publishing (Verlag)
978-3-319-30906-4 (ISBN)

Lese- und Medienproben

Biological Effects of Metal Nanoparticles - Elena Mikhailovna Egorova, Aslan Amirkhanovich Kubatiev, Vitaly Ivanovich Schvets
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This book offers a comprehensive overview of recent studies conducted on the biological effects of metal nanoparticles. It also provides a solid theoretical foundation and various metal nanoparticle synthesis methods.

Part I reviews the main chemical methods used for synthesizing metal nanoparticles in a solution and describes original method of biochemical synthesis, as well as some special procedures developed specifically for studying the biological activity of nanoparticles.

Part II analyzes current literature on the effects of metal nanoparticles observed in microorganisms and addresses the influence of silver nanoparticles obtained by biochemical synthesis on biological objects on various organization levels, namely on microorganisms,  acellular slim mold, unicellular alga, plant seeds  and mammalian cells.

The last section explains the central problems common in studies on the biological effects of metal nanoparticles and outlines potential uses of this trend in bio-nanotechnologies.

This book is aimed at specialists, professors and students aspiring to expand their knowledge about the biological activities of metal nanoparticles and nanoparticle-containing materials.

CONTENTSAbbreviations and designationsIntroductionPart IPREPARATION AND CHARACTERIZATION  OF  METAL NANOPARTICLES IN SOLUTIONSChapter 1Methods of the nanoparticles preparation in solutions LI. Introductory remarks1.2. Principles used for the choice of methods1.3. Chemical synthesis with traditional reducing agents1.3.1.General considerations1.3.2.Synthesis in water solution1.3.3.Synthesis in the two-phase system and non-aqueous solutions1.3.4.Synthesis in reverse micelles1.4. Photo-and radiation-chemical synthesis1.5. Electrochemical synthesis1.6. Biological reduction in water solution1.7. SummaryChapter 2Biochemical synthesis of metal nanoparticles2.1. Prerequisites of the method2.1.1.General information on the properties of flavonoids2.1.2.AOT/isooctane reverse micelles2.2. Cieneral scheme of the synthesis2.3. Peculiarities of the experimental procedure2.3.1.Preparation of the flavonoid micellar solution2.3.2.Extinction coefficient determination for the flavonoids in micellar solution2.4. Examples of the nanoparticles synthesis2.4.1. Silver nanoparticles2.4.2. Gold nanoparticles2.4.3. Copper nanoparticlesChapter 3Development of the biochemical synthesis for practical applicationsDetermination of the extinction coefficient for Ag nanoparticles3.1.1. Extinction coefficient of the complex3.1.2. Extinction coefficient of the nanoparticles3.2. The effect of C Qr /C Ag  relation on the formation rate and yield of silver nanoparticles3.3. Preparation of small nanoparticles with narrow size distributionChapter 4Preparation of metal nanoparticles in water solutions on the basis of biochemical  synthesis4.1. Preparation of nanoparticles as water dispersions by their transfer from micellar solution4.2. Characteristics of silver and gold nanoparticles in water solution4.2.1.Silver nanoparticles4.2.2.Gold nanoparticles4.3. Synthesis of silver and copper nanoparticles in water solution with natural stabilizers4.3.1.Starch-stabilized Ag nanoparticles4.3.2.Cyclodextrin-stabilized Ag nanoparticles4.3.3.Starch-stabilized Cu nanoparticles4.3.4.Comparison with the data found in literatureChapter 5Materials modified with metal nanoparticles5.1. Creation of liquid-phase materials with metal nanoparticles5.2. Solid materials with Ag and Cu nanoparticlesPart IIBIOLOGICAL EFFECTS OF METAL NANOPARTICLESGeneral informationChapter 6The effect of metal nanoparticles on biological objects (analysisof the literature)6.1. Metal nanoparticles effects observed on microorganisms6.1.1. Antimicrobial activities of Ag nanoparticles6.1.2. Antimicrobial activities of Cu, Au and metal oxides nanoparticles....6.2. On the mechanism of antimicrobial activities of metal nanoparticles6.3. SummaryChapter 7Antimicrobial activity of nanoparticles stabilized by synthetic surface active substance7.1. Ag and Cu nanoparticles in liquid medium7.1.1.Varnish-paint materials with biocidal properties7.1.2.Water solutions of Ag nanoparticles7.2. Solid materials and polymer films with Ag nanoparticlesChapter 8The effect of silver nanoparticles on some objects from the fungal and vegetable kingdoms8.1. Plasmodium of the acellular slime mold Physarum polycephalum8.2. Unicellular alga Chlorella vulgaris8.3. Plant seedsChapter 9The effect of silver nanoparticles on human cells in vitro and mammalians in vivo9.1. The effect of Ag nanoparticles on cells in vitro9.1.1.Toxicity of Ag nanoparticles for tumor cells. Stabilizationby AOT9.1.2.Toxicity of Ag nanoparticles for normal cells. Stabilizationby starch9.2. The effect of Ag nanoparticles on mammalian organism9.3. Inferences from the results of our studiesConclusionReferences

Erscheint lt. Verlag 26.4.2016
Zusatzinfo XVI, 292 p. 159 illus., 26 illus. in color.
Verlagsort Cham
Sprache englisch
Original-Titel Биологические Эффекты Наночастиц Металлов
Themenwelt Medizin / Pharmazie
Technik
Schlagworte Antimicrobial Activity • Biochemical Synthesis • bionanotechnology • Metal Nanoparticles • nanotechnology • Silver nanoparticles • Toxicity
ISBN-10 3-319-30906-4 / 3319309064
ISBN-13 978-3-319-30906-4 / 9783319309064
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