Aptamers

Rakesh N. Veedu

Aptamers-General Introduction. History of aptamer development. Peptide aptamers: Development and applications. Aptamer selection methodologies. Selection and application of catalytically active oligonucleotides. Aptamer Development for Therapeutic Applications. Stem-cell specific aptamers for targeted cancer therapy. Aptamers as therapeutic tools in neurological diseases. Aptamers in bacterial, viral and parasitic diseases. Aptamers for Targeted Drug Delivery & Nanotherapy. Aptamers as tools for targeted drug delivery. Aptamer-liposome conjugates: Current art and future prospects. Application of Aptamers as Biosensors. Aptamers in medical diagnosis. Aptamers for Target Specific Imaging. Molecular imaging utilizing aptamer-targeted probes. Clinical Utility Scope and Limitations of Aptamers. First therapeutic aptamer: VEGF-targeting Macugen. Aptamers: Scope, limitations and future prospects.