Biology in Stem Cell Niche (eBook)

Kursad Turksen received his Ph.D. from the University of Toronto in the area of osteoprogenitor biology and cell selection methodologies. He then did postdoctoral training at the Howard Hughes Medical Institute, University of Chicago, studying epidermal biology through use of genetically-altered mouse models. He joined the Ottawa Hospital Research Institute [previously known as the Loeb Research Institute] where he rose to the position of Senior Scientist in the Division of Regenerative Medicine. His research interests focus on stem cell biology, with a particular interest in the Claudin family of tight junction proteins and their role in epidermal lineage commitment and progression during development in health and disease. Dr. Turksen is currently Editor in Chief of the Springer journal Stem Cell Reviews and Reports in addition to serving as series editor for the Springer series Stem Cell Biology and Regenerative Medicine.

.-1 The Hematopoietic Stem Cell Niche: Cell-Cell Interactions and Quiescence.-2 THE MAMMALIAN LIMBAL STEM CELL NICHE: A COMPLEX INTERACTION BETWEEN CELLS, GROWTH FACTORS AND EXTRACELLULAR MATRIX.-3 Emerging Engineering Strategies for Studying the Stem Cell Niche.-4 Bioreactors and the Design of the Stem Cell Niche.-5 Stem Cell Niche-Radiobiological Response.-6 Impact of radiation on hematopoietic niche.-7 From neurogenic niche to site of injury: stem cell-mediated biobridge for brain repair.-8 Using Stem Cells to Promote Wound Healing: an Emerging Solution for a Clinical Problem.-9 Cancer Stem Cell Niche.- 10 Insight into Cancer Stem Cell Niche; Lessons from Cancer Stem Cell Models Generated in vitro