Insights from Imaging in Bioinorganic Chemistry

Rudi van Eldik was born in Amsterdam (The Netherlands) in 1945 and grew up in Johannesburg (South Africa). He received his chemistry education and DSc degree at the former Potchefstroom University (SA), followed by post-doctoral work at the State University of New York at Buffalo (USA) and the University of Frankfurt (Germany). After completing his Habilitation in Physical Chemistry at the University of Frankfurt in 1982, he was appointed as Professor of Inorganic Chemistry at the Private University of Witten/Herdecke in 1987. In 1994 he became Professor of Inorganic and Analytical Chemistry at the University of Erlangen-Nürnberg, from where he retired in 2010. At present he is Professor of Inorganic Chemistry at the Jagiellonian University in Krakow, Poland, and Visiting Professor of Inorganic Chemistry at the N. Copernicus University in Torun, Poland. His research interests cover the elucidation of inorganic and bioinorganic reaction mechanisms, with special emphasis on the application of high pressure thermodynamic and kinetic techniques. In recent years his research team also focused on the application of low-temperature rapid-scan techniques to identify and study reactive intermediates in catalytic cycles, and on mechanistic studies in ionic liquids. He is Editor of the series Advances in Inorganic Chemistry since 2003. He serves on the Editorial Boards of several chemistry journals. He is the author of over 880 research papers and review articles in international journals and supervised 80 PhD students. He has received honorary doctoral degrees from the former Potchefstroom University, SA (1997), Kragujevac University, Serbia (2006), Jagiellonian University, Krakow, Poland (2010), University of Pretoria, SA (2010), and Ivanovo State University of Chemistry and Technology, Russia (2012). He has developed a promotion activity for chemistry and related experimental sciences in the form of chemistry edutainment presentations during the period 1995-2010. In 2009 he was awarded the Federal Cross of Merit (‘Bundesverdienstkreuz’) by the Federal President of Germany, and the Inorganic Mechanisms Award by the Royal Society of Chemistry (London). His hobbies include music, hiking, jogging, cycling and motor-biking. He is the father of two and grandfather of four children. After attending Grammar Schools, Colin D. Hubbard read Chemistry at the University of Sheffield in England, earning honours Bachelors, and Doctor of Philosophy degrees, the latter with R.G. Wilkins and S.F.A. Kettle. Postdoctoral Research followed at MIT and Cornell (G.G. Hammes) and the University of California, Berkeley, (J.F. Kirsch). He accepted a position as Assistant Professor of Chemistry at the University of New Hampshire, Durham in 1967, and proceeded to Associate, Full and Emeritus status. In 1994 he joined the group of Rudi van Eldik as Visiting Professor and Research Associate, first at the University of Witten-Herdecke and subsequently at the University of Erlangen-Nürnberg, Germany. From 1998 – 2001 he served as a Research Manager at Unilever Research, Colworth, England. Since 2002 he has been a co-editor for Advances in Inorganic Chemistry (Volumes 54, 61, 65, 68 & 70), and a writer of review articles principally on the application of high hydrostatic pressure in inorganic chemistry reactions for mechanism diagnosis. He has spent Sabbaticals at the University of Kent, Canterbury, England, (E.F. Caldin), the University of Alberta, Edmonton, Canada, (H.B. Dunford), the University of Leicester, England (J. Burgess) and the University of Seville, Spain, (F. Sanchez).

1. Opportunities and Challenges for Metal Chemistry in Molecular Imaging. From Gamma Camera Imaging to PET and Multimodality Imaging Richard Southworth, Rafael Torres Martin de Rosales, Levente K. Meszaros,Michelle T. Ma, Gregory E. D. Mullen, Gilbert Fruhwirth, Jennifer D . Young, Cinzia Imberti, Julia Bagunya-Torres, Erica Andreozzi and Philip J. Blower 2. Molecular Magnetic Resonance Imaging Probes Based on Ln3+ Complexes Célia Bonnet and Éva Tóth 3. Luminescent Iridium(III) and Rhenium(I) Complexes as Biomolecular Probes and Imaging Reagents Kenneth Kam-Wing Lo 4. Metalloporphyrins for Medical Imaging Applications Francesca Bryden and Ross W. Boyle 5. Macrocyclic Bifunctional Chelators and Conjugation Strategies for Copper-64 Radiopharmaceuticals Brett M. Paterson and Paul S. Donnelly 6. Development of Trackable Anticancer Agents Based on Metal Complexes Ewen Bodio, Pierre Le Gendre, Franck Denat and Christine Goze 7. Advanced Chelator Design for Metal Complexes in Imaging Applications: Radiopharmaceuticals, Protein Targeting and Conjugation Benjamin P. Burke, Johanna Seemann and Stephen J. Archibald 8. Radiometallo-Labelled Peptides in Tumor Diagnosis and Targeted Radionuclide Therapy Subhani M. Okarvi and Helmut R. Maecke 9. Labelling of Graphene, Graphene Oxides and of their Congeners: Imaging and Biosensing Applications of Relevance to Cancer Theranostics James A. Tyson, David Gonzalez Calatayud, Vincenzo Mirabello, Boyang Mao and Sofia I. Pascu 10. The Chemistry of Monovalent Copper in Solutions of Pure and Mixed Non-aqueous Solvents Dip Gill and Vivek Pathania