Heat Shock Protein-Based Therapies (eBook)

ContentsContributorsPrefaceSECTION I: HEAT SHOCK PROTEIN HSP27-BASED THERAPIES1 HSP27 as a Therapeutic Target of Novel Inhibitors and Dietary Phytochemicals in CancerElena Arechaga-Ocampo and César López-Camarillo2 Heat Shock Protein 27 (HSP27, HSPB1) is Up-Regulated by Targeted Agents and Confers Resistance to Both Targeted Drugs and ChemotherapeuticsDaniele Musiani, John D. Konda, Simona Pavan, Erica Torchiaro, Jessica Erriquez, Martina Olivero and Maria F. Di Renzo3 Heat Shock Proteins and Cancer: Plant Based TherapyEvren Önay-UcarSECTION II: HEAT SHOCK PROTEIN HSP60-BASED THERAPIES4 Chaperonotherapy for Alzheimer’s Disease: Focusing on HSP60Francesco Cappello, Antonella M. Gammazza, Silvia Vilasi, Maria G. Ortore, Pier L. San-Biagio, Claudia Campanella, Andrea Pace, Antonio P. Piccionello, Giulio Taglialatela, Everly C. De Macario and Alberto J. l. Macario5 Secreted and Circulating Cell Stress Proteins in the Periodontal DiseasesBrian Henderson, Nikos Donos, Luigi Nibali and Frank KaiserSECTION III: HEAT SHOCK PROTEIN HSP70-BASED THERAPIES6 The Role of Heat Shock Protein 70 in Infection and Immunity Jose Rey-Ladino, Abiola Senok, Abdullah Sarkar and Ahlam Al Shedoukhy             7 Potential Cytoprotective Effects of Heat Shock Proteins to Skeletal Muscle John P. Vardiman, Philip M. Gallagher and Jacob A. Siedlik8 Heat Shock Proteins in Triple-Negative Breast Cancer (TNBC) TreatmentPunit Kaurunit Kaur, Tarundeep arundeep Singh, Moses Galukandealukande, Sunil Krishnanrishnan and Alexzander A. A. Asealexzander Asea9 Heat Shock Proteins in Multiple Sclerosis Pathogenesis: Friend or Foe? Rosaria Tinnirello, Giuseppina Turturici, Gabriella Sconzo, Walter Spinello, Alexzander A. A. Asea and Fabiana Geraci 10 New Indications for HSP90 and HSP70 Inhibitors as Antiviral Drugs Matthew K. Howe and Timothy A. J. Haystead 11 Potential Applications of Nanoparticles for Hyperthermia Caio C. Quini and Sunil Krishnan SECTION IV: HEAT SHOCK PROTEIN HSP90-BASED THERAPIES12 Gene Therapy Against HSP90: Glucocorticoid Receptor-Assisted Cancer TreatmentSusanta S. Adhikari, Sujan K. Mondal and Rajkumar Banerjee13 Potential of HSP90 Inhibitors to Treat Neurofibromatosis-Related TumorsJeremie Vitte and Marco Giovannini14 Role of Heat Shock Protein 90 in the Cause of Various Diseases: A Potential Therapeutic TargetSubhankar Paul 15 HSP90 Inhibitor-Based Strategies for Cancer Therapy: Advancing Toward Clinical ImpactDavid A. Proia and Richard C. Bates16 Molecular Survival Strategies of Organisms: HSP and Small Molecules for Diagnostics and Drug DevelopmentAndreas Kirschning, Johanna-Gabriela Walter, Frank Stahl, Emilia Schax, Thomas Scheper, Pooyan Aliuos and Carsten Zeilinger17 Targeting Heat Shock Proteins in Colorectal CancerSheah L. Lee, Nina C. Dempsey-Hibbert, Dale Vimalachandran, Terence D. Wardle, Paul Sutton and John H. H. WilliamsIndex