Liposomes in Analytical Methodologies

Katie A. Edwards is a scientist and lecturer at Cornell University. She earned her MS and PhD in toxicology from Cornell University and BS in chemistry from Clarkson University. Her work has primarily focused on the advancement of liposomes as analytical tools, utilizing her background in organic synthesis, lipid formulation, and novel biorecognition strategies to develop high-throughput laboratory-based methods and point-of-care diagnostics for analytes of environmental, national security, and clinical interest.

The analytical utility of liposomes: from the past to the present. Applications of liposomes in lateral flow assays. Application of liposomes in proteome microarrays for the study of lipid-protein interactions. Functional polydiacetylene liposomes as self-signaling and signal amplifying bio-and chemical sensor and sensor array. Taking advantage of liposomes in microfluidic systems. Redox liposomes in the development of electrochemical sensors. Coupling liposome-encapsulated nucleic acids with the polymerase chain reaction: a generic assay platform for high-sensitivity analyte detection. Magnetic liposomes in imaging and analysis. Liposome-based methodologies to assess pharmacokinetic parameters of drugs. Liposomes in capillary electromigration techniques. Fluorescent dye-encapsulating liposomes for cellular visualization.