- Provides strategies for the development of safe and efficacious novel formulations for various modalities of biologics, vaccines and for cancer therapy
- Highlights novel cases from current clinical trials as well as marketed products
- Reviews overall successes and challenges in the development of novel formulations, including new molecular targets for the treatment of diseases, design of target-specific therapies, regulatory considerations, individualized therapies
Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad community of scientists, students and clinicians. Written by leading authors across academia and industry, this book covers important topics such as unique drug delivery devices, non-parenteral delivery trends, novel approaches to the treatment of cancer, immunotherapy and more. It includes real-world cases and examples which highlight formulations with therapeutic proteins, monoclonal antibodies, peptides and biobetters, as well as cases on novel vaccines formulations including evolving pathogens, novel modalities of vaccines, universal vaccines. This book is a thorough and useful resource on the development of novel biologics, vaccines and cancer therapies. Provides strategies for the development of safe and efficacious novel formulations for various modalities of biologics, vaccines and for cancer therapy Highlights novel cases from current clinical trials as well as marketed products Reviews overall successes and challenges in the development of novel formulations, including new molecular targets for the treatment of diseases, design of target-specific therapies, regulatory considerations, individualized therapies
List of Contributors
Reinaldo Acevedo, Research and Development vice-presidency of Finlay Institute, Havana, Cuba
Juan C. Almagro, CTI-Boston, Pfizer, Inc., Boston, MA, USA
Manal Alsaadi, University of Tripoli, Faculty of Pharmacy, Tripoli, Libya
Chantal C.M. Appeldoorn, to-BBB Technologies B.V., Leiden, The Netherlands
Alexandra Beumer Sassi, Biopharm R&D, GlaxoSmithKline, King of Prussia, PA, USA
Akhilesh Bhambhani, Merck Research Laboratories, Bioprocess R&D, Formulation Development, West Point, PA, USA
Catherine M. Bollard, Children’s National Health System, Washington DC, USA
Kim Braz-Gomes, Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Randall J. Brezski, Principal Scientist, Biologics Research, Janssen R&D, LLC, USA
Andrew Buchanan, Antibody Discovery and Protein Engineering, MedImmune, Cambridge, UK
Danilo Casimiro, Merck Research Laboratories, Vaccine Research, West Point, PA, USA
Divya Chandra, Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
Maurizio Chiriva-Internati, Texas Tech University, Health Science Center, Lubbock, TX, USA
Beth-Ann Coller, Merck Research Laboratories, Vaccine Research, Global Clinical Development, North Wales, PA, USA
Conrad Russell Y. Cruz, Children’s National Health System, Washington DC, USA
Marco de Boer, to-BBB Technologies B.V., Leiden, The Netherlands
Robert De Rose, Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia
Sucheta D’Sa, Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Bernadette D’Souza, Department of Pharmaceutical Sciences, McWhorter School of Pharmacy, Social and Administrative Sciences, Samford University, Birmingham, AL, USA
Marissa D’Souza
Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Georgia Institute of Technology, Biomedical Engineering Program, Atlanta, GA, USA
Martin J. D’Souza, Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Nigel D’Souza, Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Mauro Ferrari
Houston Methodist Research Institute, Houston, TX, USA
Weill Cornell Medical College, New York, NY, USA
Valerie A. Ferro, University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Science, Glasgow, UK
Pieter J. Gaillard, to-BBB Technologies B.V., Leiden, The Netherlands
Rikhav P. Gala, Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Deborah A. Garside, Imperial College London, Faculty of Medicine, London, UK
Ayman Gebril, University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Science, Glasgow, UK
Werner Gladdines, to-BBB Technologies B.V., Leiden, The Netherlands
Ana Maria Gonzalez-Angulo, Department of Breast Medical Oncology, Department of Systems Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
Paul Hamblin, Biopharm R&D, GlaxoSmithKline, King of Prussia, PA, USA
Qing-Yu He, Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China
Jon Heinrichs, Merck Research Laboratories, Vaccine Research, West Point, PA, USA
Erica Jackson, College of Medicine, University of South Florida, Tampa, FL, USA
Pankaj Karande, Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
Stephen J. Kent, Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia
Sreekumar Kodangattil, CTI-Boston, Pfizer, Inc., Boston, MA, USA
Dimitrios Lamprou, University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Science, Glasgow, UK
Kenneth Lundstrom, Pan Therapeutics, Lutry, Switzerland
Sara Movassaghian, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA, USA
Nihal S. Mulla, Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Alexander B. Mullen, University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Science, Glasgow, UK
Radhika Nagarkar, Biopharmaceutical Development, KBI Biopharma, Inc., Durham, NC, USA
Lakshmy Nair, Department of Breast Medical Oncology, Department of Systems Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
Natalie Nimmo, University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Science, Glasgow, UK
Ashwin C. Parenky, Mercer University, College of Pharmacy, Vaccine Nanotechnology Laboratory, Atlanta, GA, USA
Brianna Oliver, College of Medicine, University of South Florida, Tampa, FL, USA
Ernesto Oviedo-Orta, Novartis Vaccines and Diagnostics, Vaccines Research, Siena, Italy
Teresa Ramirez-Montagut, Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA
Charani Ranasinghe, John Curtin School of Medical Research, Australian National University, Canberra, Australia
Arie Reijerkerk, to-BBB Technologies B.V., Leiden, The Netherlands
Jefferson D. Revell, Antibody Discovery and Protein Engineering, MedImmune, Cambridge, UK
Jaap Rip, to-BBB Technologies B.V., Leiden, The Netherlands
Haifa Shen
Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, USA
Weill Cornell Medical College, New York, NY, USA
Hatem Soliman, Moffitt Cancer Center and Research Institute, Women’s Oncology and Experimental Therapeutics, Tampa, FL, USA
Bin Sun
Southern Medical University
Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China
Krishna Suri, Houston Methodist Research Institute, Houston, TX, USA
Jan ter Meulen, Immune Design, Seattle, WA, USA
Vladimir P. Torchilin, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University,...
Erscheint lt. Verlag | 30.12.2014 |
---|---|
Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
Medizin / Pharmazie ► Pharmazie | |
Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
Technik | |
Wirtschaft | |
ISBN-10 | 0-12-416661-X / 012416661X |
ISBN-13 | 978-0-12-416661-5 / 9780124166615 |
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