The Pharmaceutical Studies Reader

Sergio Sismondo is Professor of Philosophy and Sociology at Queen’s University, Canada. His current work, including a number of recent articles, explores the pharmaceutical industry’s development and deployment of clinical research, focusing on intersections of marketing and science. He is the author and co-author of a number of books, including An Introduction to Science and Technology Studies, Second Edition (Wiley Blackwell, 2010) and The Art of Science (2003). He is Editor of the journal Social Studies of Science. Jeremy A. Greene is Elizabeth Treide and A. McGehee Harvey Chair in the History of Medicine at Johns Hopkins University. His recent work focuses on the ways in which the development and consumption of therapeutics interact with our understandings of what it means to be sick or healthy, normal or abnormal. His broader research interests focus on the history of disease, the history of global health, and the history of the pharmaceutical industry and its interactions with medical research, clinical practice, and public health.  He is the author of Generic: The Unbranding of Modern Medicines (2014) and Prescribing by Numbers: Drugs and the Definition of Disease (2007), as well as co-editor of Prescribed: Writing, Filling, Using, and Abusing the Prescription in Modern America (2012).

Acknowledgements vii

1 Introduction 1
Jeremy A. Greene and Sergio Sismondo

Part I Pharmaceutical Lives 17

2 The Pharmaceuticalisation of Society? A Framework for Analysis 19
Simon J. Williams, Paul Martin and Jonathan Gabe

3 Pharmaceutical Witnessing: Drugs for Life in an Era of Direct]to]Consumer Advertising 33
Joseph Dumit

Part II New Drugs, Diseases, and Identities 49

4 Releasing the Flood Waters: Diuril and the Reshaping of Hypertension 51
Jeremy A. Greene

5 Dep®ession and ConsumŠtion: Psychopharmaceuticals, Branding, and New Identity Practices 70
Nathan Greenslit

6 BiDil: Medicating the Intersection of Race and Heart Failure 87
Anne Pollock

7 Manufacturing Desire: The Commodification of Female Sexual Dysfunction 106
Jennifer R. Fishman

Part III Drugs and the Circulation of Medical Knowledge 121

8 Following the Script: How Drug Reps Make Friends and Influence Doctors 123
Adriane Fugh]Berman and Shahram Ahari

9 Getting to Yes: Corporate Power and the Creation of a Psychopharmaceutical Blockbuster 133
Kalman Applbaum

10 Pushing Knowledge in the Drug Industry: Ghost]Managed Science 150
Sergio Sismondo

11 Transcultural Medicine: A Multi]Sited Ethnography on the Scientific]Industrial Networking of Korean Medicine 165
Jongyoung Kim

Part IV Political and Moral Economies of Pharmaceutical Research 179

12 Uncommon Trajectories: Steroid Hormones, Mexican Peasants, and the Search for a Wild Yam 181
Gabriela Soto Laveaga

13 “Ready]to]Recruit” or “Ready]to]Consent” Populations? Informed Consent and the Limits of Subject Autonomy 195
Jill A. Fisher

14 Clinical Trials Offshored: On Private Sector Science and Public Health 208
Adriana Petryna

15 The Experimental Machinery of Global Clinical Trials: Case Studies from India 222
Kaushik Sunder Rajan

Part V Intellectual Property in Local and Global Markets 235

16 Intellectual Property and Public Health: Copying of HIV/AIDS Drugs by Brazilian Public and Private Pharmaceutical Laboratories 237
Maurice Cassier and Marilena Correa

17 Global Pharmaceutical Markets and Corporate Citizenship: The Case of Novartis’ Anti]Cancer Drug Glivec 247
Stefan Ecks

18 Generic Medicines and the Question of the Similar 261
Cori Hayden

Index 268