Redox Proteomics (eBook)

ISABELLA DALLE-DONNE, PHD, is Assistant Professor in the Department of Biology at the University of Milan, Italy. She has a PhD in cellular and molecular biology from the University of Milan. ANDREA SCALONI, PHD, is First Investigator at the Proteomics & Mass Spectrometry Laboratory, ISPAAM, National Research Council in Naples, Italy. He received his PhD in chemical sciences from the University of Rome "La Sapienza" in Italy. D. ALLAN BUTTERFIELD, PHD, is Alumni Professor of Chemistry and Director of the University of Kentucky Center of Membrane Sciences in Lexington, Kentucky, USA. He received his PhD in physical chemistry from Duke University.

1. Oxidatively Modified Proteins and Proteomic Technologies.

1.1 Chemical Modification of Proteins by Reactive Oxygen Species
(E. Stadtman & R. Levine).

1.2 The Chemistry of Protein Modifications Elicited By Nitric
Oxide and Related Nitrogen Oxides (D. Thomas, et al.).

1.3 Mass Spectrometry Approaches for the Molecular
Characterization of Oxidatively/Nitrosatively Modified Proteins (A.
Scaloni).

1.4 Thiol-disulfide Oxidoreduction of Protein Cysteines: Old
Methods Revisted for Proteomics (V. Bonetto & P. Ghezzi).

1.5 Carbonylated Proteins and their Implication in Physiology
and Pathology (R. Levine & E. Stadtman).

1.6 S-Nitrosation of Cysteine thiols as a Redox Signal
(Y. Zhang & N. Hogg).

1.7 Detection of Glycated and GlycoOxidated Proteins (A.
Lapolla, et al.).

1.8 MudPIT (Multidimensaional Protein Identification Technology)
for Identification of Post-translational Protein Modifications in
Complex Biological Mixtures (S. Thomas, et al.).

1.9 Use of a Proteomic Technique to Identify Oxidant-Sensitive
Thiol Proteins in Cultured Cells (M. Hampton, et al.).

1.10 ICAT (Isotope-Code Affinity Tag) Approach to Redox
Proteomics: Identification and Quantification of Oxidant-Sensitive
Protein Thiols (M. Sethuraman, et al.).

1.11 Quantitative Determination of Free and Protein-Associated
3-nitrotyrosine and S-nitrosothiols in the Circulation by Mass
Spectrometry and Other Methodologies: A Critical Review and
Discussion from the Analytical and Review Point of View (D.
Tsikas).

2. Cellular Aspects of Protein Oxidation.

2.1 The Covalent Advantage: A New Paradigm for Cell Signaling
Mediated by Thiol Reactive Lipid Oxidation Products (D. Dickinson,
et al.).

2.2 Early Molecular Events During Response to Oxidative Stress
in Human Cells by Differential Proteomics (G. Tell).

2.3 Oxidative Damage to Proteins: Structural Modifications and
Consequences in Cell Function (E. Cabiscol & J. Ros).

2.4 Oxidative Damage and Cellular Senescence: Lessons from
Bacteria and Yeast (T. Nyström).

3. Redox Proteomic Analysis in Human Diseases.

3.1 Proteins as Sensitive Biomarkers of Human Conditions
Associated with Oxidative Stress (I. Dalle-Donne, et al.).

3.2 Degradation and Accumulation of Oxidized Proteins in
Age-Related Diseases (P. Voss & T. Grune).

3.3 Redox Proteomics: A New Approach to Investgate Oxidative
Stress in Alzheimer's Diseases (D. Butterfield, et al.).

3.4 Oxidized Proteins in Cardiac Ischemia-Reperfusion (J.
Brennan & P. Eaton).

3.5 Proteome Anaylsis of Oxidative Stress: Glutathionyl
Hemoglobin in Diabetic and Uremic Patients (T. Niwa).

3.6 Glyco-Oxidative Biochemistry in Diabetic Renal Injury (T.
Miyata).

3.7 Quantitative Screnning of Protein Glycation, Oxidation, and
Nitration Adducts by LC-MS/MS: Protein Damage in Diabetes, Uremia,
Cirrhosis, and Alzheimer's Disease (P. Thornalley).

3.8 Protein Targets and Functional Consequences of Tyrosine
Nitration in Vascular Disease (L. Baker, et al.).

3.9 Oxidation of Artery Wall Proteins by Myeloperoxidase: A
proteomics Approach (T. Vaisar & J. Heinecke).

3.10 Oxidative Stress and Protein Oxidation in Pre-Eclampsia (M.
Raijmakers, et al.).

3.11 The Involvement of Oxidants in the Etiology of Chronic
Airway Diseases: Proteomic Approaches to Identify Redox Processes
in Epithelial Cell Signal and Inflammation (A. van der Vliet, et
al.).

3.12 Sequestering Agents of Intermediate Reactive Aldehydes as
Inhibitors of Advanced Lipoxidation End-Products (ALEs) (M. Carini,
et al.).

"...a major book...readers interested in mass spectrometry methods
in proteomics will find much that is of interest here." (Journal
of the American Society for Mass Spectrometry, March 2007)

"Every laboratory that uses redox proteomics in both clinical
and academic research should possess a copy of this excellent
book." (Doody's Health Services)

"...highly recommended as a reference text...Redox
Proteomics is thought to be a milestone in this field..."
(Biotechnology Journal, March 2007)