High-Density Lipoproteins (eBook)

Anatol Kontush, BSc (Hons), PhD, is Research Director at the Dyslipidemia and Atherosclerosis Research Unit of the National Institute of Health and Medical Research (INSERM) at the Pitié-Salpêtrière Hospital, Paris, France. An award-winning scientist, Dr. Kontush has authored more than 100 original papers and book chapters. M. John Chapman, BSc, PhD, DSc, FESC, is President of the European Atherosclerosis Society and Director of the Dyslipidemia and Atherosclerosis Research Unit of the National Institute of Health and Medical Research (INSERM) at the Pitié-Salpêtrière Hospital in Paris, France, affiliated with the medical faculty of the Pierre and Marie Curie University, Paris. He has authored more than 400 articles and book chapters.

Dedication.

Contents.

Abbreviations.

Preface.

Acknowledgements.

Section 1. Normal functional HDL.

Chapter 1.1 Composition.

Chapter 1.2 Heterogeneity.

Chapter 1.3 Structure.

1.4 Metabolism.

1.5 Epidemiology of HDL-C.

Chapter 1.6 Genetics.

Chapter 1.7 Biological activities.

Section 2. Functionally defective HDL.

Chapter 2.1 Altered composition.

Chapter 2.2 Abnormal metabolism.

Chapter 2.3 Impaired biological activities.

Section 3. Therapeutic normalization of subnormal levels and defective biological activities of HDL.

Chapter 3.1 Enhancement of HDL formation and normalization of intravascular HDL remodeling.

Chapter 3.2 Combination therapies.

Chapter 3.3 Other pharmacological approaches.

Chapter 3.4 Lifestyle modifications.

Conclusions and perspectives.

"In summary, the need for this book is immense: It is an
encyclopedia where everyone working in or near the field can
quickly find the fact or reference they need. It is a textbook one
can give to a student on the first day in the lab. It is a novel
that can be read when running out of controversies in your own
field." (ChemMedChem, 1 April 2013)