Domino Reactions in Organic Synthesis (eBook)

Lutz F. Tietze studied chemistry at the universities of Freiburg and Kiel, Germany and obtained his doctorate under the supervision of Prof. B. Franck in 1968. He then worked as a research associate with Prof. G. Büchi at MIT, Cambridge, USA, as well as with Prof. A. Battersby in Cambridge, UK. Since 1978 he has been Professor and Head of the Institute of Organic and Biomolecular Chemistry at the Georg-August-University in Göttingen. His research focuses on the development of efficient and selective synthetic methods, combinatorial chemistry, the total synthesis of natural products and the design of new selective anticancer agents. Professor Tietze has been awarded several prizes, including the award for his book on "Reactions and Syntheses" by the Fonds der Chemischen Industrie, the Grignard-Wittig Prize of the Société Française de Chimie and the highly prestigious Emil Fischer Medal of the German Chemical Society. He is President of the German Zentralverband der Chemie and a member of the Council of the German Research Association. He has over 360 papers, 31 patents and three books to his name. Gordon Brasche, born in 1976 in Wernigerode, Germany, studied chemistry at the University of Göttingen, gaining his diploma and doctorate under the supervision of Prof. Tietze with a thesis on the synthesis of new highly active analogous of spinosynes. During his doctorate he worked as a teaching assistant for medical and advanced organic chemistry students. Kersten Matthias Gericke, born in 1976 in Wilhelmshaven, Germany, studied chemistry at the University of Göttingen. He gained his diploma and doctorate under Prof. Tietze, achieving several total syntheses of biological highly potent anthraquinone antibiotics. He also was a teaching assistant for medical and advanced organic chemistry students.

Introduction
Cationic domino reactions
Anionic domino reactions
Radical domino reactions
Pericyclic domino reactions
Photochemically induced domino processes
Transition metal catalysis
Domino reactions initiated by oxidation or reduction
Enzymes in domino reactions
Multicomponent reactions
Special techniques in domino reactions
Introduction
Cationic Transformations
Anionic Transformations
Radical Transformations
Transformations with Carbenes and Nitrenes
Pericyclic Transformations
Photochemical Transformations
Transition Metal Catalysed Transformations
Rearrangements
Fragmentations
Reductions
Oxidations

"The book is nicely produced with very clear schemes. The text is concise but also a good read at the same time. This is a book that all serious synthetic organic chemists should add to their personal library...Domino reactions are one of the emerging philosophies in planning organic synthesis and their use should now be considered in every chemical synthesis whether in the laboratory or in industry - this book is an excellent guide." Chemistry World

"The book is nicely produced with very clear schemes. The text is concise but also a good read at the same time. This is a book that all serious synthetic organic chemists should add to their personal library...Domino reactions are one of the emerging philosophies in planning organic synthesis and their use should now be considered in every chemical synthesis whether in the laboratory or in industry - this book is an excellent guide." Chemistry World

"... Das vorliegende Buch haben Experten der organischen Synthesechemie zusammengestellt; es legt den Wissensstand auf dem Gebiet der Dominoreaktionen erstmals geschlossen dar. ... Alle Kapitel sind vorbildlich mit ausgewählten Literaturzitaten - punktuell sogar bis 2006 - gespickt. Fazit: Den Autoren ist es gelungen, das umfangreiche Gebiet der Dominoreaktionen didaktisch schön gegeliedert zusammenzufassen. ... Das Buch ist Industriechemikern, Lehrenden mit Schwerpunkt "Synthesechemie" uneingeschränkt zu empfehlen ... In Fachbiliotheken sollte ein Exemplar nicht fehlen."
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