Production of Recombinant Proteins (eBook)

Gerd Gellissen is Senior Scientist at Rhein Biotech GmbH,Düsseldorf and Associate Professor of Microbiology at the Heinrich-Heine University of Düsseldorf. He has published approx. 130 research papers and co-authored 7 patents. Professor Gellissen is editor of the Wiley-VCH book "Hansenula polymorpha" (2002).

Foreword by Herbert P. Schweizer, Colorado State University, USA

Introduction

Key and Criteria to the Selection of an Expression Platform

BACTERIAL SYSTEMS
Escherichia coli
Pseudomonas fluorescens
Staphylococcus carnosus and other Gram-positive Bacteria

YEAST SYSTEMS
Arxula adeninivorans
Hansenula polymorpha
Pichia pastoris
Yarrowia lipolytica

FILAMENTOUS FUNGI
Aspergillus sojae
Sordaria macrospora

EUKARYOTIC CELLS
Mammalian Cells
Plant Cells

Wide-Range Integrative Expression Vectors for Fungi, Based on Ribosomal DNA Elements
Comparative Fermentation
Recombinant Hepatitis B Vaccines: Disease Characterization and Vaccine Production
Biopharmaceuticals and the Industrial Environment

"...this book is an excellent single source on expression systems. The book draws on the expertise of nearly 50 contributors from academia, research establishments and industry...The book is hardbound and well produced."
Biotechnology Advances

"This book is a remarkable source of information concerning the state-of-the-art in designing the most suitable expression system for the product of choice and will become a very valuable reference for researchers in industry as well as research institutes, and also for students due to its review nature. It is a guide for laboratories as well as scientists and graduates in adjacent scientific disciplines. In addition, the supplied information may help to improve the commercialization of these products which is enforcing an interdisciplinary collaboration of scientists of different fields and engineers."
Engineering in Life Sciences

"Fazit: Ein hochinformatives Buch, das jedem interessierten Forscher eine sehr gute Übersicht über mögliche Expressionssysteme zur Verfügung stellt."
Pharmazie in unserer Zeit

"Das Buch umfasst eine Beschreibung der verschiedenen Expressionsplattformen, außerdem Informationen zur Biologie des Wirtsorganismus, ein umfangreicher methodologischer Abschnitt sowie zahlreiche Beispiele von Proteinen, die mit Hilfe einer zugehörigen Plattform exprimiert wurden."
soziale technik