Burger's Medicinal Chemistry and Drug Discovery

VOLUME 1 Structure Based Drug-Design History of Quantitative Structure Activity Relationships Recent and Developing Trends in QSAR: From Data Analysis and Model Validation to Drug Design and Discovery Molecular Modeling in Drug Design Drug-Target Binding Forces: Advances in Force Field Approaches Combinatorial Library Design, Molecular Similarity and Diversity Applications Virtual Screening Docking and Scoring Functions/Virtual Screening Bioinformatics Chemical Information Computing Systems in Drug Discovery X-ray Crystallography Drug Discovery Electron Microscopy of Biological Macromolecules Design of Peptidomimetics Approaches to the Rational Design of Enzyme Inhibitors Chirality and Biological Activity Structural Concepts in the Prediction of the Toxicity of Therapeutical Agents Natural Products as Leads for New Pharmaceuticals Analog Design NMR and Drug Discovery Mass Spectrometry and Drug Design VOLUME 2 Combinatorial Chemistry and Multiple Parallel Synthesis Highthroughput Screening for Lead Discovery High Throughput Pharmacology The Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery Oligonucleotide Therapeutics Therapeutic Agents Acting on RNA Carbohydrate Based Therapeutics Membrane Transport Proteins and Drug Transport Allosteric Proteins and Drug Discovery Receptor Targets in Drug Discovery and Development Large Scale Synthesis Principles of Drug Metabolism Metabolic Considerations in Prodrug Design Retrometabolism-Based Drug Design and Targeting Drug Discovery: The Role of Toxicology Drug Absorption, Distribution, and Elimination The FDA and Regulatory Issues Intellectual Property in Drug Discovery and Biotechnology Nicotinic Acetylcholine Receptors Physicochemical Characterization and Principles of Oral Dosage Form Selection VOLUME 3 Cardiac Drugs: Antianginal, Vosodilators, Antiarrhythmic Diuretics and Uricosuric Agents Myocardial Infarction Agents Endogenous Vasoactive Peptides Hematopoietic Agents Anticoagulatns, Antithrombotics and Hemostatics Antihyperlipedemic Agents Oxygen Delivery via Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders Sickle Cell Anemia Iron Chelators and Therapeutic Uses Thyroid Hormones and Thyromimetics Male Sex Hormones, Analogs, and Antogonists Anti-inflammatory Steroids Female Sex Hormones, Contraceptives & Fertility Drugs Fundamentals of Steroid Chemistry and Biochemistry VOLUME 4 Peptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents Inhibitors of Gastric Acid Secretion Chemokines and Cytokine Modulators COX Inhibitors and Leukotriene Modulators Agents Acting on Prostanoid Receptors Retinoids Vitamins Life Style and Over-the-Counter Agents Radiopaques Microarrays and Gene Expression Profiling Applied to Drug Research SNPs: Single Nucleotide Polymorphisms and Pharmacogenomics Gene Therapy with Plasmid DNA Insulin and Hypoglycemic Agents VOLUME 5 Molecular Biology of Cancer Synthetic DNA-targeted Chemotherapeutic Agents and Related Tumor-Activated Prodrugs Antitumor Natural Products Radiosensitizers and Radioprotective Agents Synthetic Anti-angiogenic Agents Future Strategies in Immunotherapy Selective Toxicities Drug Resistance in Cancer Chemotherapy Antiviral Agents, DNA Antiviral Agents, RNA (Viruses other than HIV), Orthopoxviruses Rationale of Design of Anti-HIV Drugs Organ Transplantation Drugs Synthetic Antibacterial Agents Lactam Antibiotics Tetracyclines, Aminolycoside, Macrolide, and Miscellaneous Antibiotics Antimycobacterial Agents Antifungal Agents Antimalarial Agents Antiprotozoal Agents Anthelmintic Agents VOLUME 6 Andrenergics and Andrenergic Blocking Agents Cholinergics Anticholinergic Drugs CNS Stimulants Sedatives and Hypnotics Anticonvulsants Analgesics Antidepressants Antianxiety Agents Antipsychotic Agents Investigative Agents for use in Neurodegenerative Conditions Therapeutic and Diagnostic Agents for Parkinson's Disease Alzheimer's Disease: Search for Therapeutics Cognition Enhancers Drugs to Treat Eating and Body Weight Disorders