Reproductive Endocrinology and Biology -

Reproductive Endocrinology and Biology (eBook)

Edward Bittar (Herausgeber)

eBook Download: PDF
1998 | 1. Auflage
340 Seiten
Elsevier Science (Verlag)
978-0-08-054458-8 (ISBN)
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We have now reached the mid-point of our editorial task of putting together the compendium, Principles of Medical Biology, which is supposed to be composed of twenty-five modules. The present single-volume module on reproductive endocrinology and biology is in more than one respect a continuation of Module 10 (in two volumes) dealing with molecular and cellular endocrinology. In addition, it intersects, as it should, with various parts of obstetrics and gynaecology, both of which are abetted by technology. One has only to recall that the practical benefits of ultrasound in perinatal medicine and in vitro fertilisation are the outcome of the technological revolution in biomedicine. Whether we are approaching a new era in reproductive biology following the invention of animal cloning is still hard to tell. For some people, it remains an article of faith that cloning of the human being is highly probable. For others, asexual reproduction is anathema. It should surely be obvious to us all that somatic cell nuclear transfer technology (SCNTT) is going to be at its strongest in dealing with husbandry. Whether this and several social forces will alter our modern outlook, there can be little doubt.
As in diverse clinical and basic research, so in obstetrics, animals are used as a model. The data thus obtained is extrapolated, if valid, to the mother and foetus. The success of this approach is exemplified in studies carried out on sheep as a model. On the whole, it is also quite apparent that progress in the field of reproductive biology is to a large extent ascribable to the discovery in other disciplines of new hormones, as well as the introduction of new tools and recent improvements in laboratory methods including measurement of hormones.

We have now reached the mid-point of our editorial task of putting together the compendium, Principles of Medical Biology, which is supposed to be composed of twenty-five modules. The present single-volume module on reproductive endocrinology and biology is in more than one respect a continuation of Module 10 (in two volumes) dealing with molecular and cellular endocrinology. In addition, it intersects, as it should, with various parts of obstetrics and gynaecology, both of which are abetted by technology. One has only to recall that the practical benefits of ultrasound in perinatal medicine and in vitro fertilisation are the outcome of the technological revolution in biomedicine. Whether we are approaching a new era in reproductive biology following the invention of animal cloning is still hard to tell. For some people, it remains an article of faith that cloning of the human being is highly probable. For others, asexual reproduction is anathema. It should surely be obvious to us all that somatic cell nuclear transfer technology (SCNTT) is going to be at its strongest in dealing with husbandry. Whether this and several social forces will alter our modern outlook, there can be little doubt.As in diverse clinical and basic research, so in obstetrics, animals are used as a model. The data thus obtained is extrapolated, if valid, to the mother and foetus. The success of this approach is exemplified in studies carried out on sheep as a model. On the whole, it is also quite apparent that progress in the field of reproductive biology is to a large extent ascribable to the discovery in other disciplines of new hormones, as well as the introduction of new tools and recent improvements in laboratory methods including measurement of hormones.

Cover 1
Reproductive Endocrinology and Biology 6
Copyright Page 7
Contents 8
List of Contributors 10
Preface 14
Chapter 1. Sexual Differentiation of the Brain 16
Chapter 2. Hypophyseal–Gonadal Relationships in the Male 40
Chapter 3. Hypophyseal–Ovarian Relations hips 72
Chapter 4. The Biology of the Ovary 92
Chapter 5. Biology of Human Fertilization: Sperm–Egg Interactions and Early Development 118
Chapter 6. Uterine Environment during the Implantation of the Embryo 136
Chapter 7. The Pineal Gland, Melatonin, and Reproduction 156
Chapter 8. The Endocrinology of Pregnancy 170
Chapter 9. The Endocrinology of Late Pregnancy and Parturition 182
Chapter 10. Maternal Adaptation to Pregnancy 198
Chapter 11. Amniotic Dynamics 226
Chapter 12. Ultrasound in Perinatal Medicine 242
Chapter 13. Placental Toxicology 272
Chapter 14. Preeclampsia and Eclampsia 294
Chapter 15. The Premenstrual Syndrome 308
Chapter 16. How RU 486 Works 324
Chapter 17. Infertility 332
Index 348

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