Vasopressin and Oxytocin: From Genes to Clinical Applications (eBook)

Cover 1
Contents 14
List of Contributors 6
Preface 10
Acknowledgements 12
Chapter 1. The magnocellular neuronal phenotype: cell-specific gene expression in the hypothalamo-neurohypophysial system 18
Chapter 2. Estrogen modulates oxytocin gene expression in regions of the rat supraoptic and paraventricular nuclei that contain estrogen receptor-ß 32
Chapter 3. Short-term modulation of GABAA receptor function in the adult female rat 48
Chapter 4. Cholesterol and steroid hormones: modulators of oxytocin receptor function 60
Chapter 5. Central vasopressin systems and steroid hormones 74
Chapter 6. Regulation of renal salt and water transporters during vasopressin escape 92
Chapter 7. Stretch-inactivated cation channels: cellular targets for modulation of osmosensitivity in supraoptic neurons 102
Chapter 8. Glial cells in the hypothalamo-neurohypophysial system: key elements of the regulation of neuronal electrical and secretory activity 112
Chapter 9. Functional synaptic plasticity in hypothalamic magnocellular neurons 130
Chapter 10. Postsynaptic GABAB receptors in supraoptic oxytocin and vasopressin neurons 138
Chapter 11. Neurohypophyseal hormones in the integration of physiological responses to immune challenges 144
Chapter 12. Involvement of the brain oxytocin system in stress coping: interactions with the hypothalamo–pituitary–adrenal axis 164
Chapter 13. Expression of human vasopressin and oxytocin receptors in Escherichia coli 180
Chapter 14. Molecular pharmacology and modeling of vasopressin receptors 196
Chapter 15. Nonpeptide vasopressin receptor antagonists: development of selective and orally active V1a, V2 and V1b receptor ligands 214
Chapter 16. Rat vasopressin mRNA: a model system to characterize cis-acting elements and trans-acting factors involved in dendritic mRNA sorting 228
Chapter 17. Dendritic action potentials in magnocellular neurons 242
Chapter 18. Modulation of synaptic transmission by oxytocin and vasopressin in the supraoptic nucleus 252
Chapter 19. The active role of dendrites in the regulation of magnocellular neurosecretory cell behavior 264
Chapter 20. Cardiovascular regulation of supraoptic vasopressin neurons 274
Chapter 21. The central vasopressinergic system in experimental left ventricular hypertrophy and dysfunction 292
Chapter 22. Cardiovascular effects of oxytocin 298
Chapter 23. Treatment of the diabetic patient: focus on cardiovascular and renal risk reduction 306
Chapter 24. Oxytocin in parturition of guinea pigs, humans, and other species 316
Chapter 25. Oxytocin, vasopressin and atrial natriuretic peptide control body fluid homeostasis by action on their receptors in brain, cardiovascular system and kidney 326
Chapter 26. Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer 346
Chapter 27. The vasopressin receptor of corticotroph pituitary cells 362
Chapter 28. Involvement of oxytocin and vasopressin in the pathophysiology of preterm labor and primary dysmenorrhea 376
Subject Index 384