Sleep and Sleep Disorders: (eBook)

A Neuropsychopharmacological Approach
eBook Download: PDF
2009 | 2006
XIII, 309 Seiten
Springer US (Verlag)
978-0-387-27682-3 (ISBN)

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Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields.  The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives.   This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms.  Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.


Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields.  The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives.   This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms.  Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.

CONTENTS 5
EDITORS 7
CONTRIBUTORS 7
FOREWORD 12
PREFACE 13
Section I: Basic Pharmacology 14
GABAa Receptor Subtypes in Sedation and Hypnosis 15
Sleep Hippocampal Theta Rhythm and sensory Processing 22
Monoamitiergic Mechanisms in the Regulation of Sleep- Wakefulness: Special Emphasis on Preoptic Noradrenergic System 27
REM Sleep Function and Brain Monoamine Regulation: An Application of the Search Activity Concept 39
Role of Wakefulness Area in the Brainstem Reticular Formation in Regulating Rapid Eye Movement Sleep 48
The Mechanistic Relationship between NREM Sleep and Anesthesia 55
Section II: Chronopharmacology 65
Time- Dependent Psychotropic Drug Effects: Hints of Pharmacochronomics, Broader than Circadian Time Structures 66
Melatonin Interaction with BZ- GabaA Receptors: Implications for Sleep Induction 107
Melatonin: A Chronobiotic that Not Only Shifts Rhythms 112
Melatonin and Human Sleep 119
Melatonin Efficacy to Treat Circadian Alterations of Sleep in Alzheimer's Disease 123
Pharmacotherapy for Seasonal Affective Disorder 133
Use and Discontinuation of Hypnosedative Medications 139
Section III: Clinical Pharmacology 145
Long- Term Use of Sleeping PiUs in Chronic Insomnia 146
Risks of Chronic Hypnotic Use 152
Meets of Psychotropics on Driving Performance 157
Diagnosis, Pathophysiology and Treatment of Hypersomnias 162
Chronic Disease and Sleep Architecture: Pharmacotherapeutic Considerations 174
Benzodiazepines for Sedation in Infants and Children 181
The Pharmacological Management of Fatigue and Sleepiness in Affective Disorders 194
Next- Day Residual EflFects of Sleeping Medications on Driving Ability: A Review of the Literature 199
Sleep and Pain 212
Head Injuries and Sleep 221
Psvchopharmacological Management of Restless Legs syndrome and Periodic Limb Movements in Sleep 227
A Comparison of Visual Analog Scale and Categorical Ratings in Assessing the Patient's Estimate of Sleep Quality 231
The Pharmacostrateey of Treating Sleep Disorders in Parkinsonism 236
The Neuropharmacology of Nightmares 252
The Night Eating Syndrome 262
Drug Effects on Dreaming 267
Sleep Problems in Primary Care 273
SSRIs and Sleep in Man 280
Sleep and Antipsychotic Drugs in Schizophrenia Patients 285
Sleep and Epilepsy: From Interrelationships to Influence of Antiepileptic Drugs 293
Herbal Medicines and Sleep 308
INDEX 315

Erscheint lt. Verlag 6.11.2009
Zusatzinfo XIII, 309 p. 121 illus.
Verlagsort New York
Sprache englisch
Themenwelt Geisteswissenschaften Psychologie
Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
Technik
Schlagworte Brainstem • Neurology • Neuroscience • Parkinson • pathophysiology • Physiology • Psychopharmacology • therapy
ISBN-10 0-387-27682-3 / 0387276823
ISBN-13 978-0-387-27682-3 / 9780387276823
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