Cell-Cell Channels (eBook)

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2007 | 2006
XVIII, 321 Seiten
Springer New York (Verlag)
978-0-387-46957-7 (ISBN)

Lese- und Medienproben

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he biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. TThis concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap­ parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel­ ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration-as a Cell Body-these two items comprise the fundamental functional and struc­ tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.
he biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. TThis concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap- parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel- ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration-as a Cell Body-these two items comprise the fundamental functional and struc- tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.

CONTENTS 5
EDITORS 11
CONTRIBUTORS 11
PREFACE 16
Cell- Cell Channels and Their Implications for Cell Theory 18
Mating Cell-Cell Channels in Conjugating Bacteria 37
The Tetrahymena Conjugation Junction 53
Cytoplasmic Bridges in Volvox and Its Relatives 78
Vegetative Hyphal Fusion in Filamentous Fungi 99
Plasmodesmata: Cell-Cell Channels in Plants 112
Sieve- Pore Pluming Mechanisms 124
Actin and Myosin VIII in Plant Cell- Cell Channels 130
Cell- Cell Communication in Wood 146
TMV Movement Protein Targets Cell-Cell Channels in Plants and Prokaryotes: Possible Roles of Tubulin- and FtsZ-Based Cytoskeletons 159
Viral Movement Proteins Induce Tubule Formation In Plant and Insect Cells 171
Cell-Cell Movements of Transcription Factors in Plants 187
Gap Junctions: Cell-Cell Channels in Animals 195
Tunneling Nanotubes: Membranous Channels between Animal Cells 210
Cytoplasmic Bridges as Cell- Cell Channels of Genn Cells 218
Fusome as a Cell-Cell Communication Channel of Drosophila Ovarian Cyst 227
Cytonemes as Cell-Cell Channels In Human Blood Cells 246
Paracellular Pores in Endothelial Barriers 255
Channels across Endothelial Cells 261
Molecular Transfers through Transient Lymphoid Cell- Cell Channels 277
Cell-Cell Transport of Homeoproteins: With or Without Channels? 293
Virological Synapse for Cell-Cell Spread of Viruses 298
Cell-Cell Fusion: Transient Channels Leading to Plasma Membrane Merger 308
Index 327

Erscheint lt. Verlag 10.8.2007
Zusatzinfo XVIII, 321 p.
Verlagsort New York
Sprache englisch
Themenwelt Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Technik
Schlagworte Fungi • Prokaryotes • Protein • proteins • transcription • Transport • Viruses
ISBN-10 0-387-46957-5 / 0387469575
ISBN-13 978-0-387-46957-7 / 9780387469577
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