Nuclear Dynamics (eBook)

Preface: Overview of Nuclear Organization and Nuclear Dynamics 5
Contents 10
1. Visual Biology of Nuclear Dynamics: From Micro- to Nano- dynamics of Nuclear Components 12
2 Nuclear Envelope: Nanoarray Responsive to Aldosterone 49
3. Mitotic Chromosome Segregation Control 66
4. Breakdown and Reformation of the Nuclear Envelope 99
5. Functional Organization and Dynamic Aspects of Nucleoli During the Cell Cycle 117
6. Dynamics, Roles, and Diseases of the Nuclear Membrane, Lamins, and Lamin- binding Proteins 133
7. Gene Selectors Consisting of DNA-Binding Proteins, Histones, and Histone- Binding Proteins Regulate the Three Major Stages of Gene Expression 154
8. Dynamic Chromatin Loops and the Regulation of Gene Expression 185
9. Nuclear Architecture: Topology and Function of Chromatin- and Non- Chromatin Nuclear Domains 204
10-1. Regulation of Chromatin Structure by Curved DNA: How Activator Binding Sites Become Accessible 234
10- 2. Actin- Related Proteins Involved in Nuclear and Chromatin Dynamics 246
10- 3. Effects of 5- Bromodeoxyuridine on Chromatin Structure 256
10- 4. Transcriptional Modulation by Nuclear Matrix Protein P13Q/ MAT3 Associated with MAR/ SAR 262
10- 5. Breaking and Tessellating the Contiguous Nuclear Genome 270
Perspective— toward understanding the in situ genome function 277
Index 283