Recent Developments in Mass Spectrometry in Biochemistry and Medicine

Newer Aspects of the Biotransformation of Carbamazepine: Structural Characterization of Highly Polar Metabolites.- Distribution in Brain Areas of Carbamazepine and Carbamazepine-10,11-epoxide in 6-Hydroxydopamine Pretreated Rats.- Specific Ion Detection of Aryloxy Beta Blocking Drugs for Metabolic Fate Determinations-Applications to Alprenolol in Rats and Dogs.- The Use of GC-MS in Perinatal Pharmacology: The Metabolism and Pharmacokinetics of Analgesic Drugs in Mothers and Their Babies.- Studies on the Measurement of ?-Methyldopa in Pregnant Women and the Newborn Infant.- Gas Chromatography-Mass Spectrometry Identification of Some Urinary Metabolites of Thiopropamine, a New Antiulcer Agent.- Metabolism and Pharmacokinetics of Bromopride in Rat and Man.- GC and MS in the Identification of Metabolites of 5-(1-methylethyl)-1-methyl-2-nitro-l H-imidazole in Dogs.- Isolation and Identification of Oxidized Metabolites of Phenazopyridine from Rat Urine.- The GC-MS Analysis of Unchanged Suloctidil (sulocton (R)) in Plasma and Urine.- Direct Quantification of Apovincaminic Acid Ethyl Ester (cavinton (R)) in Human Plasma and Urine by Mass Fragmentography.- A Mass Fragmentographic Method for the Determination of Mescaline in Biological Fluids.- Comparative in vivo Metabolism of ?1-tetrahydrocannabinol (?1-THC), cannabidiol (CBD) and cannabinol (CBN) by Several Species.- Chemical Ionization Techniques for the Analysis of Labile Compounds: 1,3-bis-(2-chloroethyl)-1-nitrosourea Plasma Clearance and Degradation.- Metabolic Profile of Biological Constituents: (1) the Effects of Sodium Dipropylacetate on Human Urinary Acids.- Investigation of Unusual Metabolites in the Urine of a Patient with Propionic Acidemia.- Identification and Quantification of Gamma-Aminobutyric Acid in Human Cerebrospinal Fluid by Gas Chromatography- Mass Spectrometry.- A New Derivatization Approach for the Determination of Prostaglandin A1 by Mass Fragmentography.- The Use of Stable Oxygen Isotopes and Mass Fragmentography for Assessing Enzyme Activity: Phenylalanine Hydroxylase in vivo.- Brain Monoamines, Monoamine Metabolites and Enzymes in Physiological Ageing and Senile Dementia.- Ontogenic Variation of Dopamine and Norepinephrine in the Adrenal Medulla of Developing Rat. A Study by Mass Fragmentography.- Quantitation of Total Urinary N-acetylcysteine Conjugates (Mercapturic Acids) by Selected Ion Monitoring.- Quantitative Analysis of Blood Amino Acids and Fatty Acids by Direct Mass Spectrometry.- Blood Levels of Cadaverine and its Metabolites Monoacetylcadaverine and Monopropionylcadaverine in Psychotic Subgroups of Schizophrenics.- Quantitative Analysis of Free and Bound Cholesterol and Cholesterol Ester Fatty Acids in Blood by Direct Mass Spectrometry.- New Developments in the Field of Mass Spectrometry and GC-MS and Their Applications to Toxicological Analysis.- In situ Methylation and/or FD-MS: A Comparative Study of Their Usefulness in the Structure Analysis of Highly Polar Metabolites.- The Exchange of Trideuteromethyl Groups When Using Methane as a Reagent Gas in Chemical Ionisation Mass Spectrometry.- Controlled Thermal Degradation Mass Spectrometry. A Direct Approach for the Analysis of Biological and Synthetic Polymers.- Comparison of Library Search Methods with Binary Encoded Steroid Mass Spectra.- Fragmentation of Monosubstituted Cyclopentenes Under Electron Impact Mass Spectrometry.- Mass Spectrometric Investigations of Stereoisomeric 3-Substituted Tropane Derivatives.- Cyclic Alkoxythiobenzamides. Mass Fragmentation and Rearrangement Under Electron Impact.- Fragmentation of Piperazinodibenzazepines on Electron-Impact.- Isolation and Determination of Structures of Some New Diterpenoid Alkaloids in Delphinium ajacis by Mass Spectrometry.- Mass Spectrometric Studies of Algal Sterols Using an Open Tubular Capillary Column.- Open Tubular Capillary Column Gas Chromatography- Mass Spectrometry of Cholecalciferol and Its Active Metabolites.- Mass Spectral Fragmentation of C5-Substituted Barbituric Acid Derivatives.- The Mass Spectra of Permethylated Disaccharides.- Quanititative Determination of Unconjugated Pterins in Biological Extracts by Gas Chromatography-Mass Fragmentography.- Mass Spectrometry of Sialic Acids.- Direct Evidence of Epoxide Metabolic Pathway for Natural Allylbenzene Compounds in Adult Rat Liver Cell Culture.- Identification and Quantitative Determination of 2,3,7,8-Tetrachlorodibenzo-para-dioxin in Animals From a Contaminated Area.- Structure Elucidation on Hydroxylated Metabolites of Polychlorinated Aromatic Compounds by GC-MS Investigation of Their Methyl Ethers.- Detection of Polychlorodibenzodioxins in Fly Ash and Flue Gas of Municipal Incinerators.- 2,3,7,8 TCDD Monitoring in Flue Gases from an Incinerating Plant.- A Peripherally Inserted Flow Directed Catheter for Use in Continuously Monitoring Pulmonary Artery Oxygen and Carbon Dioxide Tensions.- The Effect of Acute Alkalosis on Intrahepatic Oxygen Tension as Measured in Bile.- Medical Mass Spectrometry in Simultaneous Measurement of Respiratory and Blood Gases.- Measurements of Whole Body Protein Turnover in Man with 15N-glycine.- 15N Abundance in N-Fixing and Non-N-Fixing Plants.- Isotope Effects in Metabolic Studies.- Participants.- Author Index.