New Treatments for Opiate Dependence

Susan M. Stine, MD, PhD, is Assistant Clinical Professor of Psychiatry at Yale University School of Medicine and Director of the Opiate Treatment Program at the VA Connecticut Healthcare System in West Haven. She is author of a variety of scientific publications in pre-clinical neuroscience and clinical pharmacotherapy, and serves on the editorial board of several professional journals. Thomas R. Kosten, MD, is Professor of Psychiatry at Yale University School of Medicine, where he is also Director of the Division of Substance Abuse, and Chief of Psychiatry at the VA Connecticut Healthcare System in West Haven. Coeditor of the Guilford Substance Abuse Series, he serves as editorial consultant or board member for a number of professional journals and has published over 250 papers, books, and reviews

Kosten, Stine, Introduction and Overview. Part I: Foundations for the New Interventions.Kosten, Behavioral Modesl of Opiate Abuse in Animals. Nestler, Basic Neurobiology of Opiate Addiction. Part II: Optimizing Traditional Treatments: Refining the Use of Pharmacotherapy.Stine, New Developments in Methadone Treatment and Matching Treatments to Patients. Rosen, Use of Pharmacological Agents in Opiate Detoxification. Farren, O'Malley, Rounsaville, Naltrexone and Opiate Abuse: Who Benefits From It and How to Increase Its Effectiveness. Burns, Comorbid Substance Abuse in Opiate Dependent Patients. Part III: Optimisizing Traditional Treatments: Ancillary Services and Special Populations.Avants, Ohlin, Margolin, Matching Methadone-Maintained Patients to Psychosocial Treatments. Margolin, Avants, Acupuncture for Cocaine Abuse: Research Findings Methodological Issues, and Patient-Treatment Matching. Chang, Women and Opiate Dependence. O'Connor, Selwyn, Medical Issues in the Care of Opioid-Dependent Patients.Part IV: The New Pharmacotherapies.Ling, Compton, Opiate Maintenance Therapy with LAAM. Oliveto, Kosten, Buprenorphine. Kosten, Conclusions and Future Directions in Treatment Matching.