The Cytoskeleton and Cell Motility

1 Introduction.- 2 The Molecular Components of the Cytoskeleton.- 2.1 Actin and actin-associated proteins.- 2.2 Microtubules and microtubule-associated proteins.- 2.3 Intermediate filaments.- 2.4 Summary.- 3 Movement within Cells.- 3.1 Axonal transport.- 3.2 Intracellular motility in the Protozoa.- 3.3 Cytoplasmic transport in the ovaries of hemipteran insects.- 3.4 Movement of pigment granules in chromatophores.- 3.5 Cytoplasmic streaming in plant cells.- 3.6 Summary.- 4 Mitosis.- 4.1 Basic steps of mitosis.- 4.2 The mitotic spindle: general properties and design principles.- 4.3 Organisation of spindle microtubules.- 4.4 Mechanisms of anaphase chromosome movement.- 4.5 Summary and conclusions.- 5 Cilia and Flagella.- 5.1 Distribution and waveforms.- 5.2 Basal bodies and rootlets.- 5.3 Structure of the axoneme.- 5.4 Extra-axonemal components.- 5.5 Membrane specialisations.- 5.6 Biochemical complexity of the axoneme.- 5.7 The sliding microtubule model.- 5.8 Behavioural responses of microorganisms and the control of ciliary and flagellar beating.- 6 Crawling Movements.- 6.1 Common features of crawling locomotion.- 6.2 Amoeboid movement.- 6.3 Chemotaxis.- 6.4 Tissue cell locomotion.- 6.5 Myosin and crawling locomotion.- 7 Cell Surface Motility.- 7.1 General account.- 7.2 Gliding.- 7.3 Summary.- 8 Other Mechanisms for Producing Force and Movements.- 8.1 Contractile phenomena.- 8.2 Crawling in nematode sperm.- Further Reading.