Animal Models of T Cell-Mediated Skin Diseases

Harald Renz, Universität Marburg.

Making Gene-Modified Mice.- High-Throughput Gene Knockouts and Phenotyping in Mice.- Modelling Gene-Environment Interactions in Th1- and Th2-Dominated Diseases of Laboratory Animals.- Animal Models of Experimental Asthma.- Models of Rheumatoid Arthritis.- Animal Models of Inflammatory Bowel Diseases.- Murine Models of Atopic Dermatitis.- Epicutaneous Sensitization with Allergens as an Atopic Dermatitis Model.- T-Cell Receptor Transgenic Models of Inflammatory Disorders: Relevance for Atopic Dermatitis?.- What Must a Model Display for Proof as a Model of Psoriasis?.- From Classical Mouse Models of Psoriasis to a Spontaneous Xenograft Model Featuring Use of AGR Mice.- The Psoriasis SCID Mouse Model: A Tool for Drug Discovery?.- Pro- and Anti-inflammatory Effects of IL-4: From Studies in Mice to Therapy of Autoimmune Diseases in Humans.- What Must a Model Display for Proof as a Model of Contact Dermatitis?.- Acute and Chronic Models of Allergic Contact Dermatitis: Advantages and Limitations.- Transgenic Mice Expressing IFN-? in the Epidermis Are a Model of Inflammatory Skin Disease and Systemic Lupus Erythematosus.