Interplay between Metal Ions and Nucleic Acids -

Interplay between Metal Ions and Nucleic Acids

Buch | Softcover
354 Seiten
2014
Springer (Verlag)
978-94-017-8294-4 (ISBN)
165,84 inkl. MwSt
Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.

1. Characterization of Metal Ion-Nucleic Acid Interactions in Solution. - 2. Nucleic Acid-Metal Ion Interactions in the Solid State. - 3. Metal Ion-Promoted Conformational Changes of Oligonucleotides. - 4. G-Quadruplexes and Metal Ions. - 5. Metal Ion-Mediated DNA-Protein Interactions. - 6. Spectroscopic Investigations of Lanthanide Ion Binding to Nucleic Acids. - 7. Oxidative DNA Damage Mediated by Transition Metal Ions and Their Complexes. - 8. Metal Ion-Dependent DNAzymes and Their Applications as Biosensors. - 9. Enantioselective Catalysis at the DNA Scaffold. - 10. Alternative DNA Base Pairing through Metal Coordination. - 11. Metal-Mediated Base Pairs in Nucleic Acids with Purine- and Pyrimidine-Derived Nucleosides. - 12. Metal Complex Derivatives of Peptide Nucleic Acids.

Reihe/Serie Metal Ions in Life Sciences ; 10
Zusatzinfo XXXIV, 354 p.
Verlagsort Dordrecht
Sprache englisch
Maße 155 x 235 mm
Themenwelt Schulbuch / Wörterbuch
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Chemie Analytische Chemie
Naturwissenschaften Chemie Anorganische Chemie
Naturwissenschaften Chemie Organische Chemie
Sozialwissenschaften Pädagogik
Technik Maschinenbau
Technik Umwelttechnik / Biotechnologie
Schlagworte biosensors • DNA • metal ion-nucleic acid interactions • Peptide nucleic acids (PNA • RNA
ISBN-10 94-017-8294-6 / 9401782946
ISBN-13 978-94-017-8294-4 / 9789401782944
Zustand Neuware
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