Dermatotoxicology, Sixth Edition -

Dermatotoxicology, Sixth Edition

Buch | Hardcover
1232 Seiten
2004 | 6th New edition
Taylor & Francis Ltd (Verlag)
978-0-415-28862-0 (ISBN)
199,95 inkl. MwSt
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Completely revised and updated, the sixth edition of this reference work contains fundamental information on the mechanisms of action of toxicants on the skin, plus practical information on the varied responses of skin to specific toxicants and approaches to evaluating dermal toxicology.
For twenty-five years, Dermatotoxicology has stood as the definitive reference book in the field. A generation of toxicologists and dermatologists has consulted this volume throughout their careers, finding within it a wealth of theoretical and practical guidance.

Updated and expanded to reflect the latest developments in skin toxicology, Dermatotoxicology, Sixth Edition includes fundamental information on the mechanisms of action of toxic substances on the skin, as well as practical information on the various methods to evaluating dermal toxicity. It is unparalleled in its coverage, and this new edition broadens its scope to include chapters on:

* Barrier Creams
* Cosmetic Reactions
* UV Radiation Exposure
* Electron Paramagnetic Resonance
* Powdered Human Stratum Corneum
* Iontophoresis
* Permeability of Skin for Metal Compounds
* Current Trends in Skin Cancer Research
* Tape Stripping Method v. Stratum Corneum
* Hazardous Substances from Soil and Water
* Isolated Perfused Porcine Skin Flap
* Physiologically-based Pharmacokinetic Models

This completely revised and reworked edition constitutes a major contribution to the field of dermatotoxicology. Presenting the most modern concepts and methods in use today, researchers and clinicians will find this an invaluable resource time and time again.

CONCEPTS
New - Skin Permeability
New - Occlusion and Barrier Function
New - Percutaneous Absorption of Complex Chemical Mixtures
Anatomical Factors Affecting Barrier Function
Lipids of the Permeability Barrier
Percutaneous Absorption: Short-Term Exposure, Lag Time, Multiple Exposure, Model Variations, and Absorption from Clothing
New - Chemical Partitioning Into Powdered Human Stratum Corneum: A Useful in vitro Model for Studying Interaction of Chemical and Human Skin
New - Sensitive Skin
New - Transdermal Drug Delivery System
New - Iontophoresis
Irritant Dermatitis (Irritation)
Allergic Contact Dermatitis
New - Irritant Contact Dermatitis Versus Allergic Contact Dermatitis
Molecular Basis of Allergic Contact Dermatitis
Systemic Contact Dermatitis
New - Permeability of Human Skin to Metals And Paths for Their Diffusion
Photoirritation (Phototoxicity, Phototoxic Dermatitis)
Chemically Induced Scleroderma
Chemical Agents that Cause Depigmentation
Sulfur Mustard: A Chemical Vesicant Model
Carcinogenesis: Current Trends in Skin Cancer Research
Retinoids and Their Mechanisms of Toxicity
New - Skin Disorders Caused by Cosmetics in China
New - Drug Induced Ocular Phototoxicity
New - Water: Is It An Irritant?
New - Sodium Lauryl Sulfate In Dermatotoxicology
New - Barrier Creams

METHODS
Methods for in vitro Percutaneous Absorption
New - Tape Stripping Method and Stratum Corneum
Percutaneous Absorption of Hazardous Substances from Soil and Water
Isolated Perfused Porcine Skin Flap 32. Physiologically-Based Pharmacokinetic Modeling
Methods for in vitro Skin Metabolism Studies
Transdermal Drug Delivery Systems: Dermatologic and Other Adverse Reactions
Predictive Toxicology Methods for Transdermal Delivery Systems
Animal, Human, and in vitro Test Methods for Predicting Skin Irritation
Analysis of Structural Change in Intercellular Lipids of Human Stratum Corneum Induced by Surfactants: Electron Paramagnetic Resonance (EPR) Study
Test Methods for Allergic Contact Dermatitis in Animals
New - Test Methods for Allergic Contact Dermatitis in Humans
New - Immunoadjuvants in Prospective Testing for Contact Allergens
The Local Lymph Node Assay
Contact Urticaria and the Contact Urticaria Syndrome (Immediate Contact Reactions)
New - An Optimized in vitro Approach to Assess Skin Irritation and Phototoxicity of Topical Vehicles
Photoirritation (Phototoxicity) Testing in Humans
New - Measuring and Quantifying Ultraviolet Radiation Exposure
New - Use of Pig Skin Preparations in Novel Diffusion Cell Arrays to Measure Skin Absorption and to Evaluate Potential Chemical Toxicity
New - Determination of Subclinical Changes of Barrier Function
Assessing the Validity of Alternative Methods for Toxicity Testing
New - Animal Models for Immunologic and Nonimunologic Contact Urticaria
New - Diagnostic Tests in Dermatology: Patch and Photopatch Testing and Contact Urticaria Cosmetic Reactions
New - Evaluating Efficacy of Barrier Creams: in vitro and in vivo Models
New - Light-induced Dermal Toxicity: Effects on the Cellular and Molecular Levels.

Erscheint lt. Verlag 25.2.2004
Zusatzinfo 13 Halftones, black and white; 100 Tables, black and white
Verlagsort London
Sprache englisch
Maße 156 x 235 mm
Gewicht 1792 g
Themenwelt Schulbuch / Wörterbuch Lexikon / Chroniken
Medizin / Pharmazie Medizinische Fachgebiete Dermatologie
Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
ISBN-10 0-415-28862-2 / 0415288622
ISBN-13 978-0-415-28862-0 / 9780415288620
Zustand Neuware
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