Handbook of Toxicology

Michael J. Derelanko, PhD, DABT, FATS, has spent most of his career as a toxicologist in the pharmaceutical and chemical industries. He most recently was director of nonclinical drug safety assessment for Adolor Corporation where he contributed to the discovery and development of novel drugs for nearly ten years. Prior to that, as manager of toxicology and risk assessment for Honeywell International, he supported the company’s chemical businesses for over two decades. He currently is employed by Critical Path Services, a Knoell company, where he provides expertise in toxicology and hazard communication. Carol S. Auletta, DABT, RAC, MBA, has worked in toxicology research for more than 30 years. She is board certified in toxicology by the American Board of Toxicology and in regulatory affairs by the Regulatory Affairs Professionals Society. Carol has spent her career in the CRO industry and currently serves as a senior director in safety assessment and the director of program management at Huntingdon Life Sciences in East Millstone, New Jersey.

Laboratory Animal Management. General Toxicology. Dermal Toxicology. Ocular Toxicology. In Vitro Methods for the Prediction of Ocular and Dermal Toxicity. Inhalation Toxicology. Neurotoxicology. Immunotoxicology. Renal Toxicology. Developmental and Reproductive Toxicity. Juvenile Toxicology. Endocrine Toxicology. Genetic Toxicology. Carcinogenesis. Histopathology. Clinical Pathology. Metabolism and Toxicokinetics of Xenobiotics. Human Clinical Toxicology. Chemical Toxicology. Pharmaceutical Toxicology. Safety Pharmacology. Risk Assessment. Regulatory Toxicology. Appendix A: LD50 Values. Appendix B: Tables of Comparative Anatomical, Physiological, and Biochemical Data. Appendix C: Mathematics, Symbols, Physical Constants, Conversions, and Statistics. Appendix D: Calculations, Preparation, and Properties of Substances Used in Toxicology. Appendix E: Design and Performance of Toxicology Studies. Appendix F: Organizations and Agencies. Appendix G: Acronyms. Appendix H: Academic Programs in Toxicology. Appendix I: Physical/Chemical Information. Glossary. Index.