The HDL Handbook -

The HDL Handbook

Biological Functions and Clinical Implications

Tsugikazu Komoda (Herausgeber)

Buch | Hardcover
296 Seiten
2010
Academic Press Inc (Verlag)
978-0-12-382171-3 (ISBN)
147,15 inkl. MwSt
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Brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases.
The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.

Dr. Komoda is a visiting professor at Toho University School of Medicine in Japan. He has extensive expertise with research in alkaline phosphatase, amylase, and oxidized HDL. He co-operated the intestinal alkaline phosphatase at Washington University School of Medicine in St. Louis, Missouri. He is the recipient of the Kodama Memorial Award from Japanese Society of Electrophoresis.

Introduction



Role of phospholipid transfer protein (PLTP) in HDL remodelling and Atherosclerosis
The role of CETP in HDL metabolism
The physiological role of CETP in HDL molecule metabolism
HDL and reverse cholesterol transport: Physiological modulation
Serum Paraoxonase PON1 and its interactions with HDL: Relationship between PON1 and oxidative stress
Paraoxonase PON1 and its interaction with HDL: Molecular structures of PON1 and HDL
Apoliopoprotein A-I mutations
The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling
HDL and its mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease
Sterol efflux by ABCA1 and ABCG1
Possible roles of oxidized HDL: Structural change of HDL particle by oxidative modification and its contribution to vascular diseases
Pre¿1-HDL: Conversion to and from spherical ¿-migrating HDL in human plasma
Determination of circulating native and denaturated HDL concentrations and its clinical implications
 

Verlagsort San Diego
Sprache englisch
Maße 152 x 229 mm
Gewicht 650 g
Themenwelt Schulbuch / Wörterbuch Lexikon / Chroniken
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizin / Pharmazie Medizinische Fachgebiete Laboratoriumsmedizin
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
ISBN-10 0-12-382171-1 / 0123821711
ISBN-13 978-0-12-382171-3 / 9780123821713
Zustand Neuware
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