Alcohol Intoxication and Withdrawal I

Section I. Basic Mechanisms of Tolerance and Physical Dependence.- 1. Biological Models of Alcohol Tolerance and Physical Dependence.- 2. Neurochemical Aspects of Tolerance to and Dependence on Ethanol.- 3. A Role for Tetrahydroisoquinoline Alkaloids as False Adrenergic Neurotransmitters in Alcoholism.- 4. Addiction to Barbiturates and Ethanol: Possible Biochemical Mechanisms*.- Section II. Biochemical Aspects.- 1. Possible Role of Microsomal Changes Induced by Ethanol Intake in the Development of Tolerance and Dependence.- 2. Effects of Ethanol on Liver Metabolism*.- 3. Tryptophan Pyrrolase in Ethanol Administration and Withdrawal.- 4. The Metabolic Basis of Ethanol Toxicity.- 5. Biochemical Changes in Mitochondria as a Mechanism in Metabolic Tolerance to Ethanol.- 6. Hypothalamic-Pituitary-Adrenal Function in Chronic Alcoholics.- 7. Influence of Two Tetrahydrocannabinols (THC's) on the Activity of Biotransformation Enzymes.- Section III. Experimental Studies in Animals.- 1. Chronic Ingestion Techniques for the Production of Physical Dependence of Ethanol.- 2. Alcohol Oral Self-Administration in Rats: Attempts to Elicit Excessive Intake and Dependence.- 3. Evaluation of a Polydipsia Technique to Induce Alcohol Consumption in Monkeys*.- 4. Effects of Electrical Stimulation of the Lateral Hypothalamus on Ethanol Consumption.- Section IV. Experimental Studies of Sleep.- 1. Chronic Alcoholism, Alcohol and Sleep.- 2. Correlation of Urinary Biogenic Amines with Sleep Stages in Chronic Alcoholization and Withdrawal.- 3. Sleep Changes Induced by 4 and 6 Days of Experimental Alcoholization and Withdrawal in Humans.- 4. Hallucinations During Experimental Intoxication*.- 5. Sensory Superactivity, A Preliminary Report on an Hypothetical Model for an Hallucinogenic Mechanism in Alcohol Withdrawal*.- Section V. Human Experimental Studies (Excluding Sleep).- 1. Short-Term Memory Function in Alcohol Addicts During Intoxication*.- 2. The Effects of Alcohol on the Somatosensory Evoked Potentials in Man*.- 3. Affective Changes During 6 Days of Experimental Alcoholism and Subsequent Withdrawal.- 4. An Improved Quantitative System for Assessing the Acute Alcoholic Psychoses and Related States (TSA and SSA)*.- 5. Observations on the Prevalence of the Signs and Symptoms Associated with Withdrawal During Continuous Observation of Experimental Intoxication and Withdrawal in Humans.- 6. Recovery Function and Clinical Symptomatology in Acute Alcoholization and Withdrawal.