Biochemistry of Vision

Preface 1 Structure of the Eye I. Transparent Tissues II. Uvea III. Retina IV. Differentiation of Ocular Tissues References 2 Properties of Biomembranes I. Lipids II. Proteins III. Fluidity IV. Protein-Protein Interaction V. Liposomes References 3 Rod Outer Segment Membranes I. The Fluid Nature of Rod Membranes II. Disposition of Rhodopsin in the Membrane III. Phospholipids of Rod Membranes References4 Photochemistry I. Energy of Photons II. Spin States of Electrons III. Electronic Orbitals and Energy States IV. Photochemical Energy Transfer V. Absorption Spectrum and Absorption Parameters References 5 Structure and Spectral Properties of Retinal Isomers I. Isomerism II. Spectroscopy References 6 Chromophore of Rhodopsin I. Retinal II. Spectral Properties of Rhodopsin References 7 Intermediates Formed by Photobleaching of Visual Pigments I. Hypsorhodopsin II. Bathorhodopsin III. Lumirhodopsin IV. Metarhodopsins V. Energetics VI. lodopsin References8 Purification and Properties of Rhodopsin I. Extraction and Purification of Rhodopsin II. Preparation of Rod Outer Segments and Rod Disks III. Chemical Properties of Rhodopsin IV. Physical Properties References 9 Metabolism and Functions of Retinol and Its Derivatives I. Biosynthesis of Retinol II. Transport of Retinol (Retinol Binding Protein) III. Retinol Binding Protein within the Cell IV. Functions of Retinol and Its Derivatives References 10 Metabolism of the Retina and Pigmented Epithelium I. Vascular Systems in the Eye II. Metabolism of the Pigmented Epithelium III. Metabolism of the Retina References 11 Bacteriorhodopsin and Halorhodopsin I. Bacteriorhodopsin II. Halorhodopsin III. Evolutionary Significance References 12 Cell Biology of Photoreceptor Membranes I. Synthesis and Breakdown of Photoreceptor Membranes II. Assembly of Cell Membranes III. Assembly of Disk Membrane References 13 Cellular Receptors and Signal Transmission I. General Mechanisms of Signal Transmission II. Other Mechanisms References 14 Electrophysiology and Neurotransmitters I. Basic Aspects II. Retinal Neurons III. Neurotransmitters in the Nervous System IV. Neurotransmitters in the Retina References 15 Visual Excitation I. Ca2+ Model II. Biochemical Model References16 Biochemistry of Photoreceptor Disorders I. Retinitis Pigmentosa II. Gyrate Atrophy of the Choroid and Retina III. Uveoretinal Autoimmune Diseases References Index