Influenza Pathogenesis and Control - Volume I (eBook)
VIII, 444 Seiten
Springer International Publishing (Verlag)
978-3-319-11155-1 (ISBN)
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Richard W. Compans is a Professor of Microbiology and Immunology and Scientific Director of Influenza Pathogenesis and Immunology Research Center, Emory University, School of Medicine, Atlanta, GA, USA and a series editor and volume editor of several volumes with Current Topics in Microbiology and Immunology. Michael B.A. Oldstone is a Professor at the Department of Immunology and Microbial Science at the Scripps Research Institute, La Jolla, CA, USA and a series editor and volume editor of several volumes with Current Topics in Microbiology and Immunology.
Richard W. Compans is a Professor of Microbiology and Immunology and Scientific Director of Influenza Pathogenesis and Immunology Research Center, Emory University, School of Medicine, Atlanta, GA, USA and a series editor and volume editor of several volumes with Current Topics in Microbiology and Immunology. Michael B.A. Oldstone is a Professor at the Department of Immunology and Microbial Science at the Scripps Research Institute, La Jolla, CA, USA and a series editor and volume editor of several volumes with Current Topics in Microbiology and Immunology.
Part I: Molecular determinants of pathogenicity The Hemagglutinin - a Determinant of PathogenicityEva Böttcher-Friebertshäuser, Wolfgang Garten, Mikhail Matrosovich, and Hans Dieter Klenk Molecular determinants of pathogenicity in the polymerase complexGülsah Gabriel and Ervin Fodor Part II: Virus entry and cell tropism Receptor binding properties of the influenza virus hemagglutinin as a determinant of host rangeXiaoli Xiong, John W. McCauley, David A. Steinhauer Acid-induced membrane fusion by the hemagglutinin protein and its role in influenza virus biologyCharles J. RussellPart III: Transmission and Pandemics Pandemic Preparedness and the Influenza Risk Assessment Tool (IRAT)Nancy J. Cox, Susan C. Trock and Stephen A. Burke Avian influenza virus transmission to mammalsS. Herfst, M. Imai, Y. Kawaoka and R.A.M. Fouchier Transmission in the Guinea Pig ModelAnice C. Lowen, Nicole M. Bouvier and John Steel Enhancement of influenza virus transmission by gene reassortmentChengjun Li and Hualan Chen Swine and Influenza: A Challenge to One Health ResearchRobert E. Kahn, Wenjun Ma and Jürgen A. Richt Part IV: Animal models and pathogenesis Influenza Pathobiology and Pathogenesis in Avian SpeciesMonique S. Franҫa and Justin D. Brown Molecular determinants of influenza virus pathogenesis in miceRam P. Kamal, Jaqueline M. Katz, and Ian A. York Mammalian models for the study of H7 virus pathogenesis and transmissionJessica A. Belser and Terrence M. Tumpey Pathogenesis and vaccination of influenza A virus in swineDaniela S. Rajao, Tavis K. Anderson, Phillip C. Gauger, Amy L. Vincent Secondary Bacterial Infections in Influenza Virus Infection PathogenesisAmber M. Smith and Jonathan A. McCullers Part V: Evolution, Antigenic Variation Evolution and Ecology of Influenza A virusesSun-Woo Yoon, Richard J. Webby and Robert G. Webster Influenza A virus reassortmentJohn Steel and Anice C. Lowen Antigenic Analyses of Highly Pathogenic Avian Influenza A VirusesRuben O Donis
Erscheint lt. Verlag | 8.10.2014 |
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Reihe/Serie | Current Topics in Microbiology and Immunology | Current Topics in Microbiology and Immunology |
Zusatzinfo | VIII, 444 p. 48 illus., 42 illus. in color. |
Verlagsort | Cham |
Sprache | englisch |
Themenwelt | Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie ► Krankheiten / Heilverfahren |
Medizin / Pharmazie ► Allgemeines / Lexika | |
Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Technik | |
Schlagworte | Antigenic variation • avian influenza virus • H7N9 virus • Infectious Diseases • Influenza control • Influenza pathogenesis • Influenza transmission • Influenza virus evolution • Influenza virus infection • Pandemic risk assessment |
ISBN-10 | 3-319-11155-8 / 3319111558 |
ISBN-13 | 978-3-319-11155-1 / 9783319111551 |
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