Control of Fertility (eBook)
380 Seiten
Elsevier Science (Verlag)
978-1-4832-7088-3 (ISBN)
The book opens with an account of the sequence of processes essential to successful sexual reproduction in mammals. This is followed by separate chapters on approaches to the inhibition of spermatogenesis, ovulation, fertilization, and free ovum development. Subsequent chapters deal with blastocyst development and implantation, biological activities of compounds affecting fertility, fertility control in men and women, the inhibition of ovulation, biological properties of ovulation inhibitors in human subjects, and effectiveness and acceptability of contraception.
The Control of Fertility is concerned with the experimental control of fertility as a specific biological problem. It is, first of all, an attempt to summarize a collection of data hitherto either partially or not at all presented. Secondly, it attempts to indicate those avenues which hold promise for future investigation. Finally, it attempts an assessment of the implications of understandings and ignorances. The book opens with an account of the sequence of processes essential to successful sexual reproduction in mammals. This is followed by separate chapters on approaches to the inhibition of spermatogenesis, ovulation, fertilization, and free ovum development. Subsequent chapters deal with blastocyst development and implantation, biological activities of compounds affecting fertility, fertility control in men and women, the inhibition of ovulation, biological properties of ovulation inhibitors in human subjects, and effectiveness and acceptability of contraception.
Front Cover 1
The Control of Fertility 4
Copyright Page 5
Table of Contents 16
Dedication 6
Preface 8
Acknowledgments 12
PART I: INTRODUCTION 22
CHAPTER 1. Backgrounds 24
REFERENCES 30
CHAPTER 2. The Reproductive Processes and Their Vulnerabilities in Mammals
31
Processes in the Male 31
Processes in the Female 37
REFERENCES 45
PART II: ANIMAL STUDIES 48
CHAPTER 3. Spermatogenesis and Semen 50
Pituitary and Gonadotropin Inhibition 50
Direct Effects on Testis Tissue 57
Semen and Seminal Fluid 72
REFERENCES 74
CHAPTER 4. Ovulation 78
The Hypothalamopituitary Axis 78
Steroidal Ovulation Inhibitors 80
Antigonadotropin Assay 88
Antigonadotropins and the Hypothalamus 92
Inhibition of Exogenous Gonadotropin 96
Miscellaneous Antigonadotropic Agents 100
REFERENCES 103
CHAPTER 5. Fertilization 109
REFERENCES 120
CHAPTER 6. Free Ovum Development 124
REFERENCES 130
CHAPTER 7. Blastocyst Development and Implantation
132
Ovarian Hormones and Implantation Processes 134
Extra-ovarian Influences on Implantation 138
The Lability of Implantation Processes 142
Estrogens and Anti-estrogens 144
Antiprogestins 149
Poisons and Antimetabolites 159
Intrauterine Trauma 161
Corpus Luteum Inhibition 162
Abortion 164
REFERENCES 165
CHAPTER 8. Some Biological Activities of Compounds Affecting Fertility
171
Some Activities of Estrogens 172
Anti-estrogens 178
Estrogens and Androgens 181
The Activities of Gestagens 182
Effects on Fetuses 190
Hormones and Tumors 192
The Metabolism of Compounds Affecting Fertility 192
REFERENCES 196
PART Ill: CLINICAL STUDIES 206
CHAPTER 9.Control of Fertility in Men 208
REFERENCES 215
CHAPTER 10. Fertility in Women—Ovogenesis and Ovulation
218
Fertility Potential in Women 218
Detection of Ovulation 220
The Stimulation of Ovulation 230
REFERENCES 233
CHAPTER 11. The Inhibition of Ovulation 238
The Assay of Ovulation Inhibitors in Human Subjects 240
Contraception 247
REFERENCES 253
CHAPTER 12. Some Biological Properties of Ovulation Inhibitors in
257
Functions Associated with Reproductive Organs and Processes
258
Mammary Glands and Lactation 281
Pregnancy and Postpartum 284
Functions Associated with Other Endocrine Organs 287
Weight Gain and Aspects of Organic Metabolism 296
Hematology 298
Skin and Related Tissues 303
Psychological Effects 304
REFERENCES 308
CHAPTER 13. Some Consequences of the Application of Fertility Control 316
The Effectiveness of Contraception 316
The Acceptability of Contraception 319
REFERENCES 327
Author Index 330
Subject Index 366
| Erscheint lt. Verlag | 3.9.2013 |
|---|---|
| Sprache | englisch |
| Themenwelt | Sachbuch/Ratgeber ► Natur / Technik ► Naturführer |
| Naturwissenschaften | |
| Technik | |
| ISBN-10 | 1-4832-7088-2 / 1483270882 |
| ISBN-13 | 978-1-4832-7088-3 / 9781483270883 |
| Haben Sie eine Frage zum Produkt? |
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