Salivary Glands and Their Secretions (eBook)

Front Cover 1
Salivary Glands and their Secretions 4
Copyright Page 5
Table of Contents 10
PREFACE 6
ACKNOWLEDGMENTS 8
LIST OF PARTICIPANTS 13
INTRODUCTION 16
PART 1: COMPARATIVE ANATOMY AND ULTRASTRUCTURE 18
CHAPTER 1. COMPARATIVE ASPECTS OF STRUCTURE AND FUNCTION OF THE SALIVARY GLANDS 20
ABSTRACT 20
SALIVARY GLANDS OF INVERTEBRATES 20
SALIVARY GLANDS OF VERTEBRATES 25
REFERENCES 27
DISCUSSION 27
CHAPTER 2. ELECTRON MICROSCOPY OF INDUCED CHANGES IN THE SALIVARY GLAND OF THE RAT 30
ABSTRACT 30
INTRODUCTION 30
MATERIALS AND METHODS 31
EXPERIMENTAL PROCEDURES 31
RESULTS 32
DISCUSSION 53
REFERENCES 58
DISCUSSION 60
PART 2: FUNCTIONS AND HORMONAL CONTROL OF DUCTS AND ACINI 62
CHAPTER 3. THE ACTION OF THYROID AND ADRENAL GLANDS ON THE SUBMAXILLARY GLAND OF MICE 64
ABSTRACT 64
INFLUENCE OF ADRENAL GLAND 64
INFLUENCE OF THE THYROID GLAND 69
COOPERATION OF THYROID AND ADRENAL IN THEIR ACTION ON THE SUBMAXILLARY 75
DISCUSSION 77
REFERENCES 78
DISCUSSION 79
CHAPTER 4. HORMONAL INFLUENCES ON THE CYTOLOGY AND PHYSIOLOGY OF SALIVARY GLANDS 80
ABSTRACT 80
INTRODUCTION 80
THE PAROTID GLAND 81
THE SUBMANDIBULAR GLAND 86
THE EFFECT OF PARTIAL ADENOHYPOPHYSEAL INACTIVATION ON THE SALIVARY GLANDS 94
DISCUSSION 95
REFERENCES 95
DISCUSSION 97
CHAPTER 5. HORMONES, INANITION AND SALIVARY GLANDS 100
ABSTRACT 100
PART I. EXOCRINE GLANDS OF THE RAT IN HYPOTHYROID STATES 100
MATERIALS AND METHODS 102
RESULTS 103
PART II. ON THE PROTEASE AND CONVOLUTED TUBULES OF THE RAT SUBMAXILLARY GLAND 111
ACKNOWLEDGEMENT 119
REFERENCES 119
DISCUSSION 121
CHAPTER 6. STUDIES ON THE PHYSIOLOGY OF RAT AND MOUSE SUBMAXILLARY GLANDS 124
I. AMYLASE AND PROTEASE ACTIVITIES IN SERUM, SUBMAXILLARYGLAND, AND SUBMAXILLARY SALIVA OF RAT AND MOUSE 124
ABSTRACT 124
INTRODUCTION 124
MATERIAL AND METHODS 125
RESULTS 126
DISCUSSION 135
REFERENCES 137
CHAPTER 7. STUDIES ON THE PHYSIOLOGY OF RAT AND MOUSE SUBMAXILLARY GLANDS 138
II. THE ACTION OF TESTOSTERONE ON THE SODIUM AND POTASSIUM CONTENT OF SUBMAXILLARY SALIVA IN CASTRATE RATS AND MICE 138
ABSTRACT 138
INTRODUCTION 138
MATERIAL AND METHODS 138
RESULTS 139
DISCUSSION 140
REFERENCES 141
CHAPTER 8. STUDIES ON THE PHYSIOLOGY ON RAT AND MOUSE SUBMAXILLARY GLANDS 142
III. ON THE FUNCTION OF THE STRIATED DUCTS OF THE MAMMALIAN SALIVARY GLANDS 142
ABSTRACT 142
REFERENCES 146
DISCUSSION 147
CHAPTER 9. HORMONAL CONTROL OF THE NGF CONTENT IN THE SUBMAXILLARY GLANDS OF MICE 148
ABSTRACT 148
MATERIAL AND METHODS 149
RESULTS 150
DISCUSSION 156
REFERENCES 157
DISCUSSION 158
PART 3: NEURAL CONTROL OF SECRETION 162
CHAPTER 10. CENTRAL NERVOUS REPRESENTATION OF SALIVARY SECRETION 164
ABSTRACT 164
REFERENCES 175
DISCUSSION 177
CHAPTER 11. SECRETORY NERVES OF THE SALIVARY GLANDS 180
ABSTRACT 180
A. ON THE EXISTENCE OF TWO TYPES OF SECRETORY FIBRES 180
B. THE DOUBLE INNERVATION OF THE GLAND CELLS 182
C. A CONTINUOUS EFFECT OF THE SECRETORY NERVES 183
D. DEGENERATION SECRETION 186
REFERENCES 189
DISCUSSION 190
PART 4: WATER AND ELECTROLYTES 194
CHAPTER 12. CHANGES IN SALIVARY FLOW PRODUCED BY CHANGES IN FLUID AND ELECTROLYTE BALANCE 196
ABSTRACT 196
METHODS 197
RESULTS 198
DISCUSSION 210
REFERENCES 212
DISCUSSION 213
CHAPTER 13. KINETIC METHODS FOR THE STUDY OF SALIVARY SECRETIONS: THEIR SCOPE AND LIMITATIONS 216
ABSTRACT 216
REFERENCES 232
DISCUSSION 232
CHAPTER 14. ELECTROLYTE SECRETION BY RAT SALIVARY GLANDS IN VIVO AND IN VITRO 236
ABSTRACT 236
INTRODUCTION 236
MATERIALS AND METHODS 237
RESULTS 240
DISCUSSION 248
REFERENCES 252
DISCUSSION 253
CHAPTER 15. CALCIUM TRANSFER IN RAT SALIVARY AND LACRIMAL GLANDS 256
ABSTRACT 256
INTRODUCTION 256
MATERIALS AND METHODS 257
RESULTS 257
DISCUSSION 266
ACKNOWLEDGEMENT 268
REFERENCES 268
DISCUSSION 268
CHAPTER 16. THE EFFECT OF ADRENAL CORTICAL STEROIDS ON PAROTID SALIVARY SECRETION 272
ABSTRACT 272
INTRAVENOUS INFUSION OF ALDOSTERONE 279
INTRACAROTID IPSILATERAL INFUSION OF ALDOSTERONE 286
INTRAVENOUS INFUSION OF DOC 287
ACKNOWLEDGEMENT 296
REFERENCES 296
DISCUSSION 297
CHAPTER 17. THE ROLE OF SOME SALIVARY CONSTITUENTS IN ORAL PATHOLOGY, WITH SPECIAL REGARD TO CARIES EXPERIMENTS WITH RODENTS 300
ABSTRACT 300
METHODS 308
RESULTS 308
DISCUSSION 310
METHODS 311
RESULTS 311
GENERAL DISCUSSION 313
REFERENCES 314
DISCUSSION 315
PART 5: METHODS FOR STUDYING SECRETIONS 318
CHAPTER 18. COLLECTING SALIVA INTERMITTENTLY OVER LONG TIME PERIODS IN ANAESTHETIZED ANIMALS 320
REFERENCES 321
CHAPTER 19. TECHNIQUES FOR STIMULATING THE AURICULO-TEMPORAL NERVE AND RECORDING THE FLOW OF SALIVA 322
REFERENCE 326
CHAPTER 20. METHODS FOR COLLECTION OF RAT SALIVA 328
REFERENCES 333
PART 6: ORGANIC COMPOUNDS 334
CHAPTER 21. TRANSPORT, STORAGE AND SECRETION OF AMYLASE IN THE PAROTID GLAND OF THE RAT 336
ABSTRACT 336
REFERENCES 342
DISCUSSION 342
CHAPTER 22. COMPARISON OF SALIVARY AMYLASES WITH OTHER MAMMALIAN AMYLASES 346
ABSTRACT 346
INTRODUCTION 346
MATERIALS AND METHODS 347
RESULTS 347
DISCUSSION 348
REFERENCES 350
DISCUSSION 350
CHAPTER 23. THE TYROSINE, TRYPTOPHAN AND PROTEIN CONTENT OF HUMAN PAROTID SALIVA IN ORAL AND SYSTEMIC DISEASE. USE OF ULTRAVIOLET ABSORPTION TECHNICS 352
ABSTRACT 352
METHODS 353
RESULTS 356
DISCUSSION 367
ACKNOWLEDGMENTS 368
REFERENCES 369
DISCUSSION 370
CHAPTER 24. THE MOLECULAR STRUCTURE OF OVINE SUBMAXILLARY GLAND GLYCOPROTEIN 372
ABSTRACT 372
REFERENCES 379
DISCUSSION 380
CHAPTER 25. CHEMICAL AND IMMUNOLOGICAL STUDIES OF THE PROTEINS AND GLYCOPROTEINS OF HUMAN PAROTID SALIVA 386
MATERIALS AND METHODS 387
RESULTS AND DISCUSSION 387
SUMMARY 396
AKNOWLEDGMENT 396
REFERENCES 396
DISCUSSION 397