Strategies of Immune Regulation -

Strategies of Immune Regulation (eBook)

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2013 | 1. Auflage
558 Seiten
Elsevier Science (Verlag)
978-1-4832-7035-7 (ISBN)
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Strategies of Immune Regulation provides an overview of the state of knowledge on how immune regulation works. Many working scientists have taken the time to set down their views in one of two categories: (a) ''conventional'' short papers with standard documentation, (b) short expressions of opinion, with or without references. It is hoped that this book will act as a jumping-off point for new young workers, entering the field, who will ultimately fashion the next paradigm. The book contains 94 chapters organized into two sections. Section I begins with discussions of the general regulatory features of the immune systems. This is followed by papers on the role of the major histocompatibility complex and regulation involving the antibody molecules. The contributions in Section II cover the organization of Ig genes; antibody diversity and the development of the immune repertoire; MHC restriction; lymphocyte interactions and regulatory targets; role of the Ig receptor in triggering; function of IgD; lymphocyte maturation; idiotype regulation; and control of antiself reactions.
Strategies of Immune Regulation provides an overview of the state of knowledge on how immune regulation works. Many working scientists have taken the time to set down their views in one of two categories: (a) "e;"e;conventional"e;"e; short papers with standard documentation, (b) short expressions of opinion, with or without references. It is hoped that this book will act as a jumping-off point for new young workers, entering the field, who will ultimately fashion the next paradigm. The book contains 94 chapters organized into two sections. Section I begins with discussions of the general regulatory features of the immune systems. This is followed by papers on the role of the major histocompatibility complex and regulation involving the antibody molecules. The contributions in Section II cover the organization of Ig genes; antibody diversity and the development of the immune repertoire; MHC restriction; lymphocyte interactions and regulatory targets; role of the Ig receptor in triggering; function of IgD; lymphocyte maturation; idiotype regulation; and control of antiself reactions.

CONTRIBUTORS


Numbers in parentheses indicate the pages on which the authors’ contributions begin.

Luciano Adorini(483),,     Laboratorio di Radiopatologia, CNEN, CSN Casaccia, 00060 Casaccia, Rome, Italy

R. Ashman417,,     Departments of Medicine and Microbiology-Immunology, University of California at Los Angeles, Los Angeles, California 90024

Stratis Avrameas(453),,     Institut Pasteur, Paris, France

George I. Bell(3),,     Theoretical Division, Los Almos Scientific Laboratory, University of California, Los Alamos, New Mexico 87545

Baruj Benacerraf(95),,     Department of Pathology, Harvard Medical School, Boston, Massachussetts 02115

Howard Bilofsky(229),,     Bolt, Beranek, and Newman, Inc., Cambridge, Massachussetts 02138

Samuel J. Black (157, 439),,     International Laboratory for Research on Animal Diseases, P.O. Box 30709, Nairobi, Kenya

Bonnie Blomberg (271, 451),     Basel Institute for Immunology, 487 Grenzacherstrasse, CH-4005 Basel 5, Switzerland

K. Bottomly(487),,     The Institute for Cancer Research, Fox Chase, Philadelphia, Pennsylvania 19111

Peter A. Bretscher(17),,     MRC Group on Immunoregulation, Department of Immunology, University of Alberta, Edmonton, Alberta, Canada

M. Brittle(463),,     Department of Immunology, Middlesex Hospital, London, England

E.C. Butcher(77),,     Laboratory of Experimental Oncology, Department of Pathology, Stanford University Medical Center, Stanford, California 94305

John Cambier(423),,     Duke University, Verterans Administration Hospital, Building 5, Durham, North Carolina 27705

Harvey Cantor(43),,     Sidney Farber Cancer Center, Harvard Medical School, Boston, Massachussetts 02115

J. Donald Capra(233),,     Southwestern Medical School, University of Texas Health Science Center at Dallas, Dallas, Texas 75235

Robert E. Cone(395),,     Departments of Pathology and Surgery, Yale University School of Medicine, New Haven, Connecticut 06510

A. Cooke (373, 505),,     Department of Immunology, Middlesex Hospital, London W.1, England

J. Couderc(457),,     Institut d’Immuno-biologie, U.20 INSERM-LA. 143 CNRS, Hospital Broussais, 96 rue Didot, 75674 Paris, Cedex 14, France

Alastair J. Cunningham(27, 251, 287, 497),,     The Ontario Cancer Institute, The Princess Margaret Hospital, Toronto, Ontario, Canada, M4X 1K9

Terry Delovoitch(329),,     Department of Medical Research, University of Toronto, Ontario, Canada M5G 1L6

Erwin Diener(513),,     MRC Group on Immunoregulation, Department of Immunology, University of Alberta, Edmonton, Alberta, Canada

Peter C. Doherty (103, 279),,     Wistar Institute, Philadelphia, Pennsylvania 19104

Richard W. Dutton(467),,     Department of Biology, University of California at San Diego, La Jolla, California 92037

Peter Erb (345, 351),,     Institute for Microbiology, University of Basel, Petersplatz 10, CH-4003 Basel, Switzerland

Marc Feldmann (351, 393),,     Tumor Immunology Unit, Department of Zoology, University College, Gower Street, London WC1 6BT, England

James Forman(293),,     Department of Microbiology, The University of Texas Health Science Center at Dallas, Dallas, Texas 75235

H. Hugh Fudenberg(529),,     Department of Basic and Clinical Immunology, Medical School of South Carolina, Charleston, South Carolina 29403

Richard K. Gershon(43),,     Department of Pathology, Yale University Medical School, New Haven, Connecticut 06510

R.M. Gorczynski(361),,     The Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada

Michael Harvey(483),,     Department of Microbiology, University of California at Los Angeles, Los Angeles, California 90024

Leonard A. Herzenberg (157, 439),,     Department of Genetics, Stanford University School of Medicine, Stanford, California 94305

Leonore A. Herzenberg (157, 439),,     Department of Genetics, Stanford University School of Medicine, Stanford, California 94305

Geoffrey W. Hoffmann(401),,     Basel Institute for Immunology, Postfach, CH-4005 Basel 5, Switzerland

Nobumichi Hozumi(237),,     The Ontario Cancer Institute, 500 Sherbourne Street, Toronto, Ontario, Canada M4X 1K9

P.R. Hutchings(505),,     Department of Immunology, Middlesex Hospital, London W.1, England

Charles A. Janeway, Jr.(179),,     Department of Pathology, Yale University Medical School, New Haven, Connecticut 06510

Patricia P. Jones(323),,     Department of Biology, Stanford University, Stanford, California 94305

Elvin A. Kabat(229),,     The National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014

Judith A. Kapp (315),     Department of Pathology and Laboratory Medicine, The Jewish Hospital of St. Louis, St. Louis, Missouri 63110

John W. Kappler (311, 379),,     Division of Immunology, National Jewish Hospital, Denver, Colorado 80206

Doug Kilburn(363),,     Department of Microbiology, University of British Columbia Medical School, Vancouver, British Columbia, Canada

Thomas J. Kindt(233),,     National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20205

Heinz Köhler(493),,     LaRabida Institute and the Department of Pathology, The University of Chicago, Chicago, Illinois 60649

Sirkka Kontiainen (351, 393),,     Departments of Serology and Bacteriology, University of Helsinki, Haartmaninkatu 3, 00290 Helsinki, Finland

Peter H. Krammer(327),,     Institute for Immunology and Genetics, DKFZ 69, Heidelberg 1, West Germany

Julia Levy(363),,     Department of Microbiology, University of British Columbia Medical School, Vancouver, British Columbia,...

Erscheint lt. Verlag 22.10.2013
Sprache englisch
Themenwelt Sachbuch/Ratgeber Natur / Technik Naturführer
Medizin / Pharmazie
Naturwissenschaften Biologie Zoologie
ISBN-10 1-4832-7035-1 / 1483270351
ISBN-13 978-1-4832-7035-7 / 9781483270357
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