Cocaine

1. Cocaine in the 1990s.- Prevention: The Best Treatment.- The Persistence of Substance Abuse.- The Evolution of Cocaine Trafficking.- Remaining Challenges.- 2. The History of Cocaine.- The Cocaine “Miracle” of the 19th Century.- The First Cocaine “Crash”.- The Decline of Cocaine Use.- The 1960s.- The Evolution of Cocaine Use.- Other Forms of Cocaine.- The Rise of Polydrug Abuse.- The Success of Antidrug Campaigns.- Changes in Youth Attitudes.- Changes in Adult Attitudes.- Remaining Challenges.- The Legalization Debate.- 3. The Neurobiology of Cocaine.- The Role of Reward in Drug Use.- Stimulant Reinforcement.- Serotonin and Other Factors in Stimulant Reward.- Nonpharmacological Factors.- The Physiological Aspects of Drug Memory.- The Effects of Varying Routes of Administration.- The Rewarding Effects of Other Drugs.- Learning as an Outcome of Reinforcement.- Withdrawal.- The Role of Craving in Relapse.- Other Areas of Interest.- Clinical Implications.- 4. The Clinical Manifestations of Cocaine Abuse.- Acute Effects of Cocaine.- Chronic Effects of Cocaine.- Medical Complications of Cocaine Abuse.- The Medical Complications of Polydrug Abuse.- Routes of Administration.- 5. Outpatient Treatment.- Cocaine Treatment Programs.- Group Therapy.- The Role of Twelve-Step (Self-Help) Groups.- Residential Treatment.- Follow-Up Care and Family Involvement.- 6. Inpatient Treatment and Relapse Prevention.- The Benefits of Inpatient Care.- Qualities of an Inpatient Program.- Relapse Prevention.- Outcome of Treatment.- Problems with Cocaine Treatment.- 7. Pharmacological Treatments.- Pharmacological Treatment of Cocaine Craving.- Bromocriptine.- Tricyclic Antidepressants (TCAs).- Carbamazepine.- Buprenorphine.- Naltrexone.- Miscellaneous Agents.- 8. The Role of Drug Testing.-The Evolution of Drug Testing.- The “Demographics” of Drug Testing.- The Most Common Forms of Urinalysis.- Evaluation of Testing Facilities.- 9. Eating Disorders and Substance Abuse.- The Demographics of Eating Disorders.- Theories behind the Comorbidity of Eating Disorders and Substance Abuse.- Common Biological Pathways for Eating Disorders and Substance Abuse.- Treatment Implications.- 10. Physicians, the Elderly, Adolescents, and Substance Abuse.- The Medical Profession.- The Elderly and Substance Abuse.- Adolescents and Substance Abuse.- Multiple Substances of Abuse.