Werner’s Syndrome and Human Aging
Springer-Verlag New York Inc.
978-1-4684-7855-6 (ISBN)
A workshop focused on the needs of ce11 banking and 1ed to an accumu1ation of research materials both in Japan (main1y under the leadership of T. Matsumura) and in the U.S.A. (with the cooperation of Dr. Arthur Greene of the Institute of Medica1 Research).
Historical Perspective.- On Cataract in Conjunction with Scleroderma.- Werner’s Syndrome (Progeria of the Adult) and Rothmund’s Syndrome: Two Types of Closely Related Heredofamilial Atrophic Dermatoses with Juvenile Cataracts and Endocrine Features; a Critical Study with Five New Cases.- Werner’s Syndrome: A Review of its Symptomatology, Natural History, Pathologic Features, Genetics and Relationship to the Natural Aging Process.- Werner Syndrome: A Review of Recent Research with an Analysis of Connective Tissue Metabolism, Growth Control of Cultured Cells, and Chromosomal Aberrations.- Clinical, Pathological and Genetic Aspects of the Werner Syndrome and Normal Human Aging.- Genetics and Aging: Werner’s Syndrome as a Segmental Progeroid Syndrome.- Clinical, Endocrine and Metabolic Aspects of the Werner Syndrome Compared with Those of Normal Aging.- Pathology of the Werner Syndrome.- Neuropathology of the Werner Syndrome.- Werner’s Syndrome and Aging: A Reappraisal.- A Comparison of Adult and Childhood Progerias: Werner Syndrome and Hutchinson-Gilford Progeria Syndrome.- Clinical, Demographic and Genetic Aspects of the Werner Syndrome in Japan.- Immunological Aspects of the Werner’s Syndrome: An Analysis of 17 Patients.- Clinical and Metabolic Studies on the Werner’s Syndrome: With Special Reference to Disorders of Lipid and Liver Function.- Growth Control of Werner Syndrome Cells In Vitro.- Growth Characteristics of Werner Syndrome Cells in Vitro.- Studies of SV40-Infected Werner Syndrome Fibroblasts.- Experimental Studies on Werner’s Syndrome Fibroblasts.- Cell Fusion Studies in the Werner Syndrome.- Cell Fusion Studies and Biochemical Analysis of DNA Synthesis in Werner and Non-Werner Cultured Cells.- Molecular Mechanisms of Cellular Senescence: DNAMetabolism and Chromatin Change.- Histone H1 in G1 Arrested, Senescent and Werner Syndrome Fibroblasts.- Genome Reorganization During Aging of Dividing Cells.- Cellular Mechanisms of Ageing in the Werner Syndrome.- Autoradiographic Studies of DNA Replication in Werner’s Syndrome Cells.- Abnormal Fibroblast Aging and DNA Replication in the Werner Syndrome.- Extrachromosomal Circular DNA and Aging Cells.- Molecular Mechanisms of Cellular Senescence: Errors in Protein Synthesis.- Protein Synthetic Fidelity in Aging Human Fibroblasts.- Analysis of Cellular Senescence through Detection and Assessment of RNAs and Proteins Important to Gene Expression: Transfer RNAs and Autoimmune Antigens.- Cytogenetics of the Werner Syndrome.- Cytogenetic Aspects of Werner Syndrome.- A Population and Cytogenetic Study of the Werner Syndrome in Sardinia.- Connective Tissue Metabolism and Disturbances in the Werner Syndrome.- Proteoglycans in the Werner Syndrome and Aging: A Review and Perspective.- Cell Surface Changes in Senescent and Werner’s Syndrome Fibroblasts: Their Role in Cell Proliferation.- Acidic Glycosaminoglycans in Werner’s Syndrome: Studies on Levels in Tissue, Organ, Cell and Fluid.- Acidic Glycosaminoglycans of SV40-Transformed Werner’s Syndrome Cells.- Glycosaminoglycan Synthesis in Untransformed and Transformed Werner Syndrome Fibroblasts: A Preliminary Report.- Gene Action, Development and Aging: New Directions for Research in the Werner Syndrome.- The Notion of Primordial Building Blocks in Construction of Genes and Transcriptional and Processing Errors due to Random Occurrence of Oligonucleotide Signal Sequences.- Appearance of Albumin-Producing Cells in the Liver of Anabulminemic Rats on Aging and Administration of Mutagens.
Reihe/Serie | Advances in Experimental Medicine and Biology ; 190 |
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Zusatzinfo | XV, 656 p. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie | |
ISBN-10 | 1-4684-7855-9 / 1468478559 |
ISBN-13 | 978-1-4684-7855-6 / 9781468478556 |
Zustand | Neuware |
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