Hybridomas and Cellular Immortality

I. Introduction To Hybridomas.- 1 Somatic Cell Hybrids and Hybridomas.- II. Antibody Diversity And Lymphocyte Differentiation.- 2 The Nature and Origin of Antibody Diversity.- 3 Hematopoietic Tumors: Normal or Abnormal Models of Leukocyte Differentiation?.- 4 Dissection of Human Immunoregulatory T Lymphocytes: Implications for Understanding Clinical Disease.- 5 Immune (?) Interferon and Lymphotoxin Production by T Cell Lines and Hybrids.- III. Monoclonal Antibodies as Probes of Antigen Structure.- 6 Partial Structural Characterization of Human HLA-DR Subsets Using Monoclonal Antibodies.- 7 Monoclonal Antibodies for Analysis of HLA Antigens: Further Studies with the W6/32 Antibody.- IV. Monoclonal Antibodies in Diagnosis and Therapy.- 8 Monoclonal Antibodies to Hepatitis B Surface Antigen.- 9 Wandering Around the Cell Surface: Monoclonal Antibodies Against Human Neuroblastoma and Leukemia Cell Surface Antigens.- 10 Monoclonal Antibodies to Human Melanoma-Associated Antigen p97.- 11 A Biochemical and Biosynthetic Analysis of Human Melanoma-Associated Antigens with Monoclonal Antibodies.- 12 Monoclonal Antibodies to a Tumor Specific Antigen on Rat Mammary Carcinoma Sp4 and their use in Drug Delivery Systems.- 13 Monoclonal Antibody to a Tumor Specific Epitope of Murine Lymphoma Cells: Use in Characterization of Antigen and in Immunotherapy.- V. New and Relevant Methodology.- 14 Human Hybridomas.- 15 Procedures for In Vitro Immunization and Monoclonal Antibody Production.- 16 Liposome-facilitated In Vitro Induction of Primary Cell-Mediated Immunity to Human Cancer Antigens: Potential Adjunct to Hybridoma Technology.- 17 Comparison of Three Immunoassays for Screening Anti-Hepatitis B Hybridomas.- VI. Poster Abstracts.- 1. T-Lymptocyte Subsets of Rhesus Macaque as Determinedby Monoclonal Antibodies: T?, T?, T-NULL, and Histamine Receptor Bearing T Lymphocytes.- 2. Production of Human Immunoglobulin Secreting Clones Without the Use of H.A.T. Sensitive Fusion Partners.- 3. Species Distribution of Antigenic Sites on Mouse LDH-C4 Determined by Monoclonal Antibodies.- 4. A New Non-Immunoglobulin Producing Human Myeloma Cell line for Production of Hybridomas.- 5. Monoclonal Antibodies to Human Prostate and Bladder Tumor Associated Antigens.- 6. Antibody Purification by Recycling Isoelectric Focusing.- 7. Monoclonal Antibodies Against Human Ejaculated Sperm-Application in Antibody Mediated Infertility.- 8. Analysis of Peripheral Blood and Salivary Gland Lymphocytes in Sjogren’s Syndrome.- 9. A Monoclonal Antibody Which Identifies a Subpopulation of Human B Lymphocytes and Monocytes.- 10. In Vivo Localization of Tumor Associated Antigens with Radioactively Labeled Monoclonal Antibodies.- 11. Characteristics of Monoclonal Antibodies to Herpes Simplex Type 2.- 12. Type Specific Monoclonal Antibodies to Equine Infectious Anemia Virus: Development and Use in the Characterization of Canine and Feline Derived Viruses.- 13. Biochemical and Biological Analysis of Venezuelan Equine Encephalomyelitis Viruses (VEE) Using Monoclonal Antibodies.- 14. Monoclonal Antibodies Specific for Herpes Simplex Virus Type 1 Mediate Antiviral Effects In Vitro and In Vivo.- 15. Monoclonal Antibodies Against Antigens of Amastigotes and Epimastigotes of Trypanosma Cruzi.- 16. Differential Effects of Four Monoclonal Antibodies to Human ?2-Microglobulin on In Vitro Lymphocyte Functions.- 17. Selective Inhibition of Functional Sites on Cell Bound Human C3b By Monoclonal Antibodies.- 18. Generation of Monoclonal Antibodies Reacting With Human Normal and Neoplastic MammaryDuct Epithelial Cells.- 19. Resolution of Human Liver Mao A and B Using A Monoclonal Antibody Immunoaffinity Column.- 20. Isolation of Antibodies that are Specific for Human Carboxypeptidase B But Not for the Zymogen Procarboxypeptidase B by Affinity Chromatography.- 21. Dexamethasone Effects on Hybridoma Formation.- 22. Class Antigen in the Rat: Evidence for More Than One Using Monoclonal Antibodies.- 23. An Immunohistochemical Method for Large Scale Specificity Screening of Monoclonal Antibodies.- 24. Monoclonal Antibodies to Chicken Hemopoietic-Lymphoid Cellular Differentiation Antigens.- Author Index.