Hormonal Factors in Carbohydrate Metabolism, Volume 6 (eBook)

Sir Gordon Ethelbert Ward Wolstenholme OBE FRCP was a British medical doctor, and the founding director of the Ciba Foundation. He was born in Sheffield, the son of a mechanical engineer, and educated at Repton School and Corpus Christi, Cambridge.

CIBA FOUNDATION COLLOQUIA ON ENDOCRINOLOGY 5
CONTENTS 9
Foreword by the Chairman 7
Alternative routes of carbohydrate metabolism 17
Discussion 35
Nature and intracellular distribution of the enzymes con- cerned in the metabolism of the hexoses in the liver 38
Discussion 58
The enzymatic synthesis and structure of glycogen 60
Discussion 68
Hormonal influences in the synthesis of fat from carbohydrate 71
Discussion 83
The role of the anterior pituitary in the synthesis of fat from carbohydrate 86
Discussion 94
Effects of insulin and corticoids on lipogenesis in uitro 99
Discussion 108
Responses of dogs to purified growth hormone 111
Discussion 129
ACTH and growth hormone as diabetogenic factors 132
Discussion 144
Influence of the adrenal cortex on carbohydrate metabolism 154
Discussion 166
Adrenal cortex and carbohydrate phosphorylation 170
Discussion 183
Adrenocortical steroids on carbohydrate metabolism in man 186
Discussion 196
Clinical observations on metabolism in obesity 201
Discussion 213
Hormonal control of glycogen storage 215
Discussion 228
The influence of insulin on carbohydrate metabolism 233
Discussion 239
Can other fuels substitute for glucose in tissues subjected to intense insulin activity? 246
Discussion 252
Inhibitory effect of pancreas extract and H-G factor on the insulin glucose uptake of the isolated diaphragm 255
Discussion 263
Human and experimental diabetes 265
Discussion 269
Response of the liver to insulin hepatic vein catheter studies in man
Discussion 282
The insulinase and insulinase-inhibitor activity of the liver 285
Discussion 298
Estrogens, carbohydrate metabolism and mitosi 300
Discussion 312
Hormonal aspects of carbohydrate metabolism in semen and male reproductive organs 317
Discussion 326
The effect of castration and steroid therapy on seminal plasma with respect to fructose utilization by normal bull sperm 327
Discussion 338
Some endocrine studies in diabetic pregnancy 340
Pregnancy and diabetes 352
Discussion 357