Evidence Base for Diabetes Care (eBook)

William Herman Professor Herman is an internationally recognized researcher, educator, and clinician in the prevention and treatment of diabetes. He is currently the Director of the Michigan Diabetes Research and Training Center. He has given over 125 invited lectures around the world, and has published eight books, 26 book chapters and almost 150 articles in peer-reviewed journals. He was associate editor for the journals Clinical Diabetes and Diabetes Care. Professor Herman is the recipient of the American Diabetes Association's Kelly West Award for Outstanding Achievement in Epidemiology. Rhys Williams Professor Rhys Williams is Professor of Clinical Epidemiology at the University of Wales, Swansea. He is Vice-President of the International Diabetes Federation (IDF) and Chair of the IDF Task Force on Diabetes Awareness. He is also Chair of Diabetes UK's Wales Advisory Council. His main research interests relate to diabetes and the metabolic syndrome, especially their epidemiology, health services research and economics. Ann Louise Kinmonth Professor Kinmonth is the Foundation Professor of General Practice at the University of Cambridge. She has contributed through research to the management of diabetes and prevention of cardiovascular disease in general practice and is also interested in the impact of genetics on general medical practice. Nick Wareham Professor Wareham is an Honorary Consultant at Addenbrooke's Hospital, Cambridge. He is Director of the MRC Epidemiology Unit and co-Director of the Institute of Metabolic Science. His principal research interests are the aetiology and prevention of obesity and diabetes. He also leads the href="http://www.mrc-epid.cam.ac.uk/Research/Programmes/Programme_1/index.html">Aetiology of Diabetes Programme and is the Clinical Lead for the Eastern England Diabetes Local Research Network.

The Evidence Base for Diabetes Care 1
Contents 7
List of Contributors 9
1 The evidence base for diabetes care 11
Part 1: Evidence-based definition and classification 17
2 Classification of diabetes 19
3 Commentary on the classification and diagnosis of diabetes 35
Part 2: Primary and primordial prevention and early detection 39
4 Prevention of type 1 diabetes 41
5 Prevention of type 2 and gestational diabetes 59
6 The evidence to screen for type 2 diabetes 121
Part 3: Prevention of complications 145
7 The effectiveness of interventions aimed at weight loss and other effects of diet and physical activity in achieving control of diabetes and preventing its complications 147
8 What is the evidence that changing tobacco use reduces the incidence of diabetic complications? 171
9 Does intensive glycaemic management reduce morbidity and mortality in type 1 diabetes? 188
10 Does intensive glycaemic management reduce morbidity and mortality in type 2 diabetes? 199
11 Glycaemic control and other interventions in the treatment of gestational diabetes 209
12 Antihypertensive therapy to prevent the cardiovascular complications of diabetes mellitus 236
13 Does treating hyperlipidaemia with medication prevent complications? 251
14 Other cardiovascular risk factors 266
15 Prevention of the consequences of diabetes – a commentary 276
Part 4: Treatment of established complications 283
16 Treatment of diabetic retinopathy 285
17 Prevention and treatment of diabetic nephropathy: the role of blood pressure lowering 295
18 Treatment of established complications: periodontal disease 301
19 Treatment of diabetic neuropathy 327
20 Treatment of erectile dysfunction 351
21 Cardiac complications and management 365
22 The treatment of established complications: cerebrovascular disease 387
23 The management of peripheral arterial disease in patients with type 2 diabetes 403
24 Epidemiology of foot ulcers and amputations in people with diabetes: evidence for prevention 413
Part 5: Self-management, healthcare organization and public policy 429
25 What is the evidence that increasing engagement of individuals in self-management improves the processes and outcomes of care? 431
26 Delivering care to the population 448
27 Cost-effectiveness of interventions for the prevention and control of diabetes 459
28 The role of public policy 481
Index 499