Endocrine System at a Glance (eBook)

Ben Greenstein is Senior Visiting Research Fellow in the Pain Management Unit at the Royal Free School of Medicine, London Diana Wood is Director of Medical Education and Clinical Dean at the University of Cambridge School of Clinical Medicine and Addenbrooke's Hospital, Cambridge

The Endocrine System at a Glance 5
Table of Contents 7
Preface to the third edition 8
Preface to the first edition 9
Introduction 10
Chemical transmission 12
Mechanisms of hormone action: I membrane receptors 14
Mechanisms of hormone action: II Intracellular receptors 16
The hypothalamus and pituitary gland 18
Gonadotrophin-releasing hormone: a peptide hormone 20
Principles of feedback control 22
Endocrine function tests 24
Growth: I cellular growth factors 26
Growth: II Normal growth 28
Growth: III Growth hormone 30
Growth: IV Pathophysiology 32
Thyroid: I Thyroid gland and thyroid hormones 34
Thyroid: II Thyroid hormone secretion and action 36
Thyroid: III Thyroid pathophysiology 38
Adrenal gland: I Adrenal medulla 40
Adrenal gland: II Adrenocortical hormones 42
Adrenal gland: III Adrenocorticotrophic hormone (ACTH) 44
Adrenal gland: IV Cortisol and androgens 46
Adrenal gland: V Aldosterone 48
Adrenal gland: VI pathophysiology 50
Endocrine autoimmunity 52
Sexual differentiation and development: I Introduction 54
Sexual differentiation and development: II Puberty 56
Female reproduction: I menstrual cycle 58
Female reproduction: II ovarian steroids 60
Female reproduction: III Pregnancy 62
Female reproduction: IV Parturition and lactation 64
Female reproduction: V pathophysiology 66
Female reproduction: VI Contraception 68
Male reproduction: I The testis 70
Male reproduction: II Actions of androgens 72
Male reproduction: III Pathophysiology 74
Oxytocin 76
Vasopressin 78
Renin–angiotensin–aldosterone system 80
Endocrine hypertension 82
Insulin: I The pancreas and insulin secretion 84
Insulin: II Insulin action 86
Insulin: III Type 1 diabetes mellitus 88
Insulin: IV Type 2 diabetes mellitus 90
Glucagon 92
Gastrointestinal hormones 94
Energy homoeostasis: I summary 96
Energy homoeostasis: II Central control 98
Obesity: I Causes of obesity 100
Obesity: II cardiovascular and respiratory complications 102
Obesity: III insulin resistance and endocrine complications 104
Calcium: I parathyroid hormone 106
Calcium: II Calcitonin 108
Calcium: III Vitamin D 110
Bone remodelling 112
Metabolic bone disease: I paget’s disease 114
Metabolic bone disease: II primary osteoporosis 116
Metabolic bone disease: III Secondary osteoporosis 118
McQs 120
Answers 135
Appendix: Normal Values 138
Glossary 139
Index 141

"The book thus succeeds in presenting a comprehensive overview of endocrinology for students of health sciences and of clinical endocrinology. It is a concise guide as well as a revision aid. Practicing clinicians also will enjoy dipping into the book from time to time for refreshing knowledge." (J.Trop.Ped, 2011)